In models using both intact animals and isolated lungs of rats, rabbits, lambs, and dogs, application of high airway pressure and resultant lung overdistension has been shown to cause lung injury. Under pathological conditions, the more normal portions of the lung may be subjected to relative overdistension when supranormal airway pressures are used. A small animal model of lung overdistension ...

BACKGROUND Breathlessness is a common problem in chronic heart failure (CHF) patients, and respiratory muscle strength has been proposed to play an important role in causing breathlessness in these patients. OBJECTIVES The aim of this study was to investigate the relation between respiratory muscle strength and the severity of CHF, and the influence of respiratory muscle strength on abnormal ...

BACKGROUND To determine the influence of breathing maneuver and sitting posture on tidal volume (TV), respiratory rate (RR), and muscle activity of the inspiratory accessory muscles in patients with chronic obstructive pulmonary disease (COPD). METHODS Twelve men with COPD participated in the study. Inductive respiratory plethysmography and surface electromyography were used to simultaneously...

introduction: purpose of this study was the effect of different music rhythms (fast rhythm and slow rhythm) in physiological responses of health young male after an exhaustive exercise session during primary minutes of recovery period. methods: seventeen healthy male (ages: 19.76 ± 0.97 yr, height: 176 ± 6.72 cm, weight: 68.5 ±7 5.95 kg), voluntarily performed bruce protocol until exhaustion wi...

Tidal volume reduction during mechanical ventilation reduces mortality in patients with acute lung injury and the acute respiratory distress syndrome. To determine the mechanisms underlying the protective effect of low tidal volume ventilation, we studied the time course and reversibility of ventilator-induced changes in permeability and distal air space edema fluid clearance in a rat model of ...

[Purpose] The purpose of this study was to compare the effect of humidity changes on the values of pulmonary function at rest. [Subjects and Methods] This study was conducted with 30 young adults (9 males, 21 females; mean age 19.4 years). Participants' mean height was 165.1 cm, and their mean weight was 60.2 kg. The experimental setting was a laboratory in which temperature was fixed at 25 °C....

PURPOSE The 4D-CT data used for comparing a patient's ventilation distributions before and after lung radiotherapy are acquired at different times. As a result, an additional variable--the tidal volume (TV)--can alter the results. Therefore, in this paper we propose to normalize the ventilation to the same TV to eliminate that uncertainty. METHODS Absolute ventilation (AV) data were generated...

OBJECTIVES Volumetric capnography provides the standard CO2 elimination by the volume expired per respiratory cycle and is a measure to assess pulmonary involvement. Thus, the objective of this study was to evaluate the respiratory dynamics of healthy control subjects and those with cystic fibrosis in a submaximal exercise protocol for six minutes on the treadmill, using volumetric capnography ...