Background: Cerebral venous sinus thrombosis (CVST) is a potentially life-threatening condition with wide range of clinical presentations, from localized headache (the most common symptom) to mental status disturbances, seizures, and coma. Objectives: The main purpose this study was evaluate serum levels ferritin, iron, total iron binding capacity (TIBC) their possible relationship different pa...

BACKGROUND The role of inflammation in the development and progression of chronic kidney disease (CKD) in cats is not well characterized. Hepcidin is a recently discovered acute-phase protein (APP) that plays an important role in iron metabolism and contributes to the development of anemia in humans with CKD. OBJECTIVES To compare serum APP concentrations, iron status, and erythropoietin (EPO...

We established a method for fully automated measurement of total iron-binding capacity (TIBC) in serum without separation of the unbound excess iron after saturating serum transferrin. After saturation of serum transferrin with an excess amount of iron (first step), the unbound iron was eliminated by formation of a complex with ferrozine, which was used as a chromogenic reagent (second step). F...

Background In a recent Finnish study, ferritin was suggested to be an independent risk factor for acute myocardial infarction. This study suggested that high levels of iron stores might thus be atherogenic and possibly explain partly the sex difference in the incidence of ischemic heart disease. Methods and Results A randomly selected group (n=2036), men and women aged 25 to 74 years, were exam...

Mutations of the HFE and TFR2 genes have been associated with iron overload. HFE and TFR2 mutations were assessed in blood donors, and the relationship with iron status was evaluated. Subjects (N = 542) were recruited at the Hemocentro da Santa Casa de São Paulo, São Paulo, Brazil. Iron status was not influenced by HFE mutations in women and was independent of blood donation frequency. In contr...

OBJECTIVE Febrile seizure is one of the most common neurological conditions of childhood. Several theories, such as iron deficiency anemia have been proposed as the pathogenesis of this condition. The aim of this study was to find the association between iron deficiency anemia and febrile seizures in children aged 6 months to 3 years admitted in Valie Asr hospital in Zanjan. MATERIALS &METHOD...

Red meat consumption has been positively associated with colorectal cancer; however, the biological mechanism underlying this relationship is not understood. Red meat is a major source of iron, which may play a role in colorectal carcinogenesis via increased crypt cell proliferation, cytotoxicity, and endogenous N-nitrosation. In a nested case-control study within the Prostate, Lung, Colorectal...

BACKGROUND Gastroenteritis is considered one of the leading causes of morbidity and mortality in children especially in developing countries. It is a major childhood problem in Gaza and one of the most common etiologic agents of iron deficiency anemia (IDA). AIM This study was conducted to investigate possible changes in blood parameters that are associated with gastroenteritis infection amon...

Background: Gastroenteritis is considered one of the leading causes of morbidity and mortality in children especially in developing countries. It is a major childhood problem in Gaza and one of the most common etiologic agents of iron deficiency anemia (IDA). Aim: This study was conducted to investigate possible changes in blood parameters that are associated with gastroenteritis infection amon...

Aim: To obtain the clinical appraisal and haemato-biochemical alterations in cattle suffering from anaemia in Jammu division of J&K, India. Materials and Methods: 125 cattle were screened for anaemia on the basis of Haemoglobin (Hb) concentration. Blood samples were taken for estimation of Hb, packed cell volume (PCV), total erythrocyte count (TEC), mean corpuscular volume (MCV), mean corpuscul...