OBJECTIVE To evaluate thyroid function and hormonal profile in women with polycystic ovary syndrome (PCOS). METHODS A case-control study was conducted at Saad Abualila Center, Khartoum, Sudan. The cases were women with confirmed PCOS based on Rotterdam criteria. The controls were infertile women with no evidence of PCOS. The socio-demographic characteristics and medical history were gathered ...

OBJECTIVE Our aim was to demonstrate the occurrence of euthyreoid sick syndrome in patients with systemic sclerosis (SSc). Furthermore, the presence of anti-thyroid antibodies and their relationship to thyroid 5'-deiodinase activity was investigated. METHODS The activity of thyroid 5'-deiodinase was measured by 5' outer ring-deiodination using the sera of patients with SSc (n = 21), undiffere...

Autoantibodies to thyroglobulin and thyroid peroxidase are common in the euthyroid population and are considered secondary responses and indicative of thyroid inflammation. By contrast, autoantibodies to the TSH receptor are unique to patients with Graves' disease and to some patients with Hashimoto's thyroiditis. Both types of thyroid antibodies are useful clinical markers of autoimmune thyroi...

BACKGROUND AND OBJECTIVES Thyroid dysfunction is common in the elderly. We sought to explore thyroid hormone patterns in a series of elderly patients undergoing elective coronary procedures and their relation to the extent of coronary artery disease. MATERIALS AND METHODS We enrolled 81 consecutive elderly patients admitted to undergo elective diagnostic or interventional coronary procedures....

background: infections attributed to helicobacter pylori ( h. pylori ) involve almost half of the world's population. one of the effects is auto-antibody induction and cross-reaction with numerous proteins in the body. as a result of its widespread prevalence and importance, this study evaluates the associations between h. pylori and thyroid auto-antibodies. materials and methods: this study en...

Abstract Background Hashimoto’s encephalopathy (HE) is a rare but controversial syndrome showing variety of neurological and psychiatric manifestations associated with autoimmune thyroiditis. Case presentation We present case 46-year-old hypertensive female who developed acute onset behavioral symptoms mimicking affective disorder (mania). Investigations revealed high levels anti-thyroid peroxi...

Background: Intensive statin therapy was found to reduce thyroid autoimmunity in women with Hashimoto's thyroiditis. No similar data are available for other hypolipidemic agents. Methods: The participants of the study were 16 women with Hashimoto's thyroiditis and coronary artery disease. On the basis of statin tolerance, they were divided into 2 groups. 8 patients who did not tolerate high-dos...

Abstract Introduction Hashimoto's thyroiditis raises the risk for differentiated thyroid cancer (DTC) in surgical series, but role of peroxidase antibodies (TPO) remains controversial that regard. We designed present study to evaluate effect preoperative TPO titers DTC. Methods A comprehensive search was conducted PubMed, CENTRAL and Scopus databases November 2021 terms "thyroid cancer" "TPO" o...