Idiopathic thrombocytopenia purpura (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia and mucocutaneous bleeding. The former has a primary role in the diagnosis and treatment of ITP. One of the leading causes of miscounted platelets in patients who suffer from ITP is giant platelets which may indicate factitiously a severe false thrombocytopenia. Here, a case of macroth...

BACKGROUND In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocytopenia, in particular, immune-mediated thrombocytopenia (immune thrombocytopenia) that usually manifests with severe thrombocytopenia. RESULTS Sera were collected from 64 out...

amegakaryocytic thrombocytopenia (amt) is a rare cause of acquired thrombocytopenia. the pathogenesis and treatment of amt is not clearly known. here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. the patient did not respond to intravenous immunoglob...

background: immune thrombocytopenia is a hematologic disorder characterized by low platelet count and variable bleeding manifestations due to immune-mediated platelet destruction and/or suppression of platelet production. this study was performed to evaluate characteristics and clinical presentations of adult patients with immune thrombocytopenia and to explore the clinical value of platelet an...

OBJECTIVES Thrombocytopenia is defined as a platelet count of < 150 × 10⁹/L. It is a common hematologic abnormality during pregnancy. Evaluation and treatment of gestational thrombocytopenia can be both, expensive and invasive, and may result in an adverse outcome. The aim of our study was to investigate the incidence of perinatal complications in pregnancies complicated with gestational thromb...

Coronavirus pneumonia has been detected in Wuhan City since December 2019. Today, coronavirus 2019 (COVID-19) has become an epidemic worldwide. Although this disease is not fully understood, it can show different symptoms over time. One of the components involved in the body by this virus is platelets that communicate directly with several different types of viruses, including the SARS-CoV viru...

flutamide is a non-steroidal antiandrogen commonly used in the treatment of prostate cancer. severe hepatotoxicity occurs in few patients, yet may be fatal. to date, none of the reported cases of flutamide hepatotoxicity has demonstrated thrombocytopenia and chronic liver disease. we report the case of a 55-year-old male with prostatic adenocarcinoma who developed liver failure after six months...

introduction crimean-congo hemorrhagic fever (cchf) is a viral hemorrhagic fever caused by infection with a tick-borne virus from the family of bunyaviridae. this viral hemorrhagic fever is found throughout central asia, southern europe, africa and the middle east. transmission to humans occurs through contact with infected animals or tick bite. the first human cases of infectious hemorrhagic f...

background&amp; objectives: inspite of intensive worldwide efforts to reduce its transmission, malaria remains the most serious and widespread protozoal infection of humans. it is a protozoan disease transmitted by the bite of infected female anopheles mosquito. malaria has long featured prominently in the grey area between parasitology and hematology. this study has been performed to evaluate ...