Arrestin2 binding to the active but unphosphorylated luteinizing hormone/choriogonadotropin receptor (LH/CG R) in ovarian follicles is triggered by activation of ADP-ribosylation factor 6 (ARF6) and leads to uncoupling of this receptor from cAMP signaling. We sought to determine how arrestin2 binds to LH/CG R, if binding is of high affinity, and if the receptor also binds arrestin3. Desensitiza...

To comply with the International Code of Phytosociological Nomenclature (ICPN), we validate names Saturejo spinosae-Scutellarietalia hirtae , Arenarion creticae Verbascion spinosi and Lomelosio sphacioticae-Centranthetum sieberi . Two divergent interpretations Article 3i about point at issue in validation first three are discussed. Syntaxonomic reference : Bergmeier (2002), unless indicated oth...

0002-7863/82/1504-6842$01.25/0 the original alcohol substituent. Similar annulations from allylic alcohols via unsymmetrical diallyl ethers are demonstrated by Table I1 entries g-j. The requisite diallyl ethers for photoannulation of 2g-j are readily available by Williamson synthesis from the hydroxy olefin precursors indicated. It is noteworthy that the stereochemistry of the substituent R' in...

aAssociate Professor, Department of Clinical Sciences, School of Dental Medicine, University of Nevada Las Vegas. bProfessor, Restorative and Prosthetic Dentistry, College of Dentistry, The Ohio State University, Columbus, Ohio. (J Prosthet Dent 2012;108:401-403) 1 Instrument kit with available inserts, from left to right: 0.050in. hexagon straight (Zimmer part # HX1.25D), 0.048-in. 24 mmL hex ...

AIM Several published studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) are promising anticancer agents. This study examined the in vitro effect of O-alkylated NSAID hydroxamic acid derivatives 3a-i on cell survival for a panel of human tumour cell lines, their cytotoxicity on normal human fibroblasts and their antiviral activity. MATERIALS AND METHODS Established methods of ...

Communicated by David Blackwell, November 3, 1969 1. Statement of results. Let (Y, «, t^O) be a real, separable Gaussian process with stationary increments, mean 0, and F0 = 0. Let 2Q(t) be the variance of Yt and define Xt = Yt/(2Q(t)yi\ THEOREM 1. Suppose there exists a nonnegative function v(t) such that Q(s + t) Q(s) (*) lim = 1 uniformly in s t~*oo v(s + 0 "~ () and there exist positive con...

objective: recently, a wide variation has been reported in delivery of the target torque by spring-style mechanical torque limiting devices (mtlds) but the effect of aging on their accuracy has not been independently evaluated. the purpose of this study was to determine the effect of aging on the accuracy of spring-style mtlds. methods: in this in-vitro experimental study, 15 new spring-style m...

Recent studies have shown that nuclear transcription factor cyclic adenosine monophosphate response element binding protein (CREB) is overexpressed in many different types of cancers. Therefore, CREB has been pursued as a novel cancer therapeutic target. Naphthol AS-E and its closely related derivatives have been shown to inhibit CREB-mediated gene transcription and cancer cell growth. Previous...

OBJECTIVES The purpose of this study was to determine the influence of platform switching on stress distribution of two different implant systems using three-dimensional (3D) finite element models. MATERIALS AND METHODS Six 3D finite element models were created to replicate two different implant systems with peri-implant bone tissue, in which six different implant-abutment configurations were...