Despite recent advances in technique, spinal cord ischemia remains one of the most dreaded complications of thoracic aortic surgery. Recently, it has been suggested that thoracic endovascular aortic repair may decrease the risk of paraplegia. We present a case of delayed paraplegia following thoracic endovascular aortic repair that was successfully reversed on 3 separate occasions in the same p...

BACKGROUND Endovascular repair of the thoracic aorta has become an increasingly utilized therapy. Although the short-term mortality advantage over open surgery is well documented, late mortality and the impact of presenting pathology on long-term outcomes remain poorly reported. METHODS AND RESULTS A database was built from 5 prospective studies and a single institutional series. Rates of per...

Indications for and experience with placement of endovascular stent-grafts in the thoracic aorta are still evolving. Common pathologic conditions of the thoracic aorta that are amenable to stent placement include penetrating ulcers, aortic dissection, aortic aneurysms, aortic rupture, and congenital abnormalities. Advances in multidetector computed tomography (CT) permit high-quality two-dimens...

Hemoptysis is the rarest presentation of thoracic aortic aneurysm (TAA).This critical condition is one of the life-threatening medical emergencies. Even with prompt approaches, TAA can have highly terrible outcomes.   Although TAA is an almost asymptomatic condition that is accidentally discovered, imaging with contrast is the most useful modality to diagnosis it.

BACKGROUND Right thoracic curvature, rib cage deformities and aortic left shift are features of adolescent idiopathic scoliosis that are correlated with each other. We recently reported that disturbance of ribcage development results in progressive thoracic scoliosis in mice. Recently, it has been confirmed that the normal spine exhibits right thoracic curvature and rib cage deformities and tha...

INTRODUCTION We report mid-term results from the endovascular treatment of acute thoracic aortic pathologies in a single center. METHODS We retrospectively interrogated our clinical database and identified the following patients who were treated for an acute thoracic aortic pathology during a 3-year period (January 2003 to February 2006) with the deployment of a thoracic endograft: 8 male pat...

A single-center, retrospective, cohort study was performed from January 2005 to May 2019. Of 391 patients evaluated for thoracic endovascular aortic repair (TEVAR), 9 (2%) had shaggy aneurysms, defined as an ulcerated atheroma or thrombus thickness ≥5 mm protruding into the lumen and/or occupying more than two thirds of circumference on computed tomography angiography. Two nine presented with b...

BACKGROUND Endografts originally designed and approved for the treatment of thoracic aortic aneurysms have rapidly been adopted for nonapproved use in the treatment of disorders of the thoracic aorta, including aortic transection, dissection, pseudoaneurysms, and thoracoabdominal aneurysms. The purpose of this study was to evaluate the early outcomes of patients treated with thoracic endografts...

The importance of maintaining contractile function in aortic smooth muscle cells (SMCs) is evident by the fact that heterozygous mutations in the major structural proteins or kinases controlling contraction lead to the formation of aneurysms of the ascending thoracic aorta that predispose to life-threatening aortic dissections. Force generation by SMC requires ATP-dependent cyclic interactions ...