The reaction of three [FeII(TSC)2] complexes, where TSC is a pyridine-substituted thiosemicarbazone the DpT or BpT families, with H2O2 in acetonitrile solution does not result accumulation of...

Three copper(II) complexes of salicylaldehyde N(4)-phenyl thiosemicarbazone (H2L ) and two copper(II) complexes of N(4)-cyclohexyl thiosemicarbazone (H2L ) have been synthesized and characterized by different physicochemical techniques like magnetic studies and electronic, infrared and EPR spectral studies. The complexes 1⁄2ðCuL1Þ2 12H2O ð1Þ and [(CuL )2] (4) having dimeric structure. The thios...

Evaluation the Effect of Chemotherapy Drugs and Thiosemicarbazone Complexes on Expression URHC CASC15 LncRNAs in Acute Lymphoblastic Leukemia Cell Line

Anticancer drugs A series of monoand dinuclear (η-arene) ruthenium(II) complexes were prepared by reaction of thiosemicarbazone ligands derived from benzaldehyde and ruthenium(II) precursors of the general formula [Ru(η-arene)(μ-Cl)Cl]2, where arene=p-PrC6H4Me or C6H5C3H6COOH. These complexes were characterized by NMR and IR spectroscopy, ESI-mass spectrometry and elemental analysis. The molecu...

Pancreatic cancer is an aggressive neoplasm, with a mortality rate close to 100%. The most successful agent for pancreatic cancer treatment is gemcitabine, although the overall effect in terms of patient survival remains very poor. This study was initiated to evaluate a novel class of anticancer agents against pancreatic cancer. This group of compounds belongs to the dipyridyl thiosemicarbazone...