Terahertz pulsed imaging (TPI) is a recent and nondestructive technique to quantify coating thickness of pharmaceutical tablet film coatings. In this study, TPI is used for the first time to quantify the progress of an active coating process. The dosage form consisted of a push-pull osmotic system comprising a two-layer tablet core with a functional film coating and a laser drilled hole. On top...

[1] Sea ice is a very important indicator and an effective modulator of regional and global climate change. Current remote sensing techniques provide an unprecedented opportunity to monitor the cryosphere routinely with relatively high spatial and temporal resolutions. In this paper, we introduce a thermodynamic model to estimate sea and lake ice thickness with optical (visible, near‐infrared, ...

BACKGROUND Optical Coherence Tomography (OCT) imaging is being increasingly used in clinical practice for the monitoring of papilloedema. The aim is to characterise the extent and location of the Retinal Nerve Fibre Layer (RNFL) Thickness automated segmentation error (SegE) by manual refinement, in a cohort of Idiopathic Intracranial Hypertension (IIH) patients with papilloedema and compare thi...

AIMS To evaluate the scanning retinal thickness analyser (RTA), a novel non-invasive imaging instrument, in diagnosing and quantitatively characterising diabetic macular oedema, and to investigate the relation between central macula thickness measured by RTA and other clinical examinations. METHODS Central macular thickness was measured using the RTA in 40 normal subjects and 60 patients with...

Introduction Perforated sheets are used in a number of industrial applications e.g. the shadow masks in colour monitor and television tubes. Their design requires the characterization of the deformation behaviour of a perforated sheet containing a large number of tiny holes. In practice, the holes are varying through the sheet thickness, however, in modelling this inhomogeneity is mostly ignore...

Background Increased left ventricular (LV) mass is a strong predictor of cardiovascular events and mortality and is common among patients with type 2 diabetes. Carotid intima-media thickness (CIMT) is commonly used to monitor progression of coexisting atherosclerosis. However, the relationship between the progression of LV mass and vascular changes in the carotid and coronary arteries remains p...

This paper presents the calculation of the perceived color of dielectric films on silicon. A procedure is shown for computing the perceived color for an arbitrary light source, light incident angle, and film thickness. The calculated color is converted into RGB parameters that can be displayed on a color monitor, resulting in the generation of electronic color charts for dielectric films. This ...

The ability of certain polypeptides to aggregate into long, thin fibrils called amyloid structures is associated with multiple protein folding disorders and is also a major problem in biotechnological and pharmaceutical applications. Here, QCM-D has been used to monitor the changes in thickness and viscoelastic properties of multilayer amyloid deposition in situ for the first time. This provide...

Little is known of the in vivo structural changes of large arteries in uncomplicated hypertension. Therefore, we measured the intima-media thickness and lumen diameter of common carotid and femoral arteries by a computerized ultrasonographic technique in 25 normotensive and 25 never treated hypertensive men of similar age (from 25 to 72 years). The intraobserver variability of carotid and femor...