We prove the reducibility of 1-D quantum harmonic oscillators in $\mathbb R$ perturbed by a quasi-periodic time potential $V(x,\omega t)$ under following conditions, namely there is $C>0$ such that \begin{equation*} |V(x,\theta)|\le C,\quad|x\partial_xV(x,\theta)|\le C,\quad\forall~(x,\theta)\in\mathbb R\times\mathbb T_\sigma^n. \end{equation*} The corresponding perturbation matrix $(P_i^j(\the...