Penicillium sp. FO-125, a soil isolate, was found to produce a new antifungal antibiotic complex named atpenin. Three components A4, A5 and B were isolated from the fermentation broth of the producing strain by solvent extraction, silica gel column chromatography and HPLC. The molecular formula of atpenins A4, A5 and B were determined to be C15H22NO5Cl, C15H21NO5Cl2 and C15H23NO5, respectively,...

conclusions non-albicans candida should be considered as significant pathogens in burned patients with candidemia. results twenty-seven samples (6.7%) of the blood cultures from 13 patients (12%) were positive for candida species. candida parapsilosis (38%) and c. tropicalis (38%) were the most commonly found candida species, followed by c. albicans (15%) and c. guilliermondii (15%) in the pati...

AS-3-Ketosteroid isomerase of Pseudomonas testosteroni is a homogeneous and crystalline enzyme that promotes the irreversible conversion of A5-3-ketosteroids to A4-3-ketosteroids (1, 2). This enzyme is one of the most active catalytic proteins known, since each mole (molecular weight 40,800) converts 16.7 x lo6 moles of A5-androstene-3, 17-dione (I) to A4-androstene-3, 17dione (II) per minute a...

vulvovaginal candidiasis is caused by the increasing number of candida species as normal flora in the vagina. to assess the transmission rout as well as to determine the suitable antifungal drugs for treatment, the exact identification of candida species is crucial. therefore, earlier detection of infection allows quick initiation of antifungal therapy with a greater probability for improved su...

Background and Purpose: Candida species constitute an important group of opportunistic fungi, which cause various clinical diseases. Considering the resistance of some Candida species to conventional antifungal agents, treatment of such cases may be challenging and complicated. The purpose of this study was to evaluate and compare the antifungal activities of Euphorbia macroclada latex and fluc...

argumentation frameworks [Dun95] take a very simple view on argumentation as they do not presuppose any internal structure of an argument. Abstract argumentation frameworks only consider the interactions of arguments by means of an attack relation between arguments. Definition 1 (Abstract Argumentation Framework). An abstract argumentation framework AF is a tuple AF = (Arg,→) where Arg is a set...

Several atoxigenic Aspergillus flavus isolates, including some being used as biocontrol agents, and one toxigenic isolate were surveyed for the ability to produce extracellular xylanolytic and pectinolytic hydrolases. All of the tested isolates displayed good production of endoxylanases when grown on a medium utilizing larch xylan as a sole carbon substrate. Four of the tested isolates produced...

background and purpose: the incidence of fungal infection as well as candidemia has increased significantly, contributing to morbidity and mortality in the developed countries. the alarming increase in infections with multidrug resistant bacteria is due to overuse of a broad spectrum antimicrobials, which leads to over growth of candida spp.; thus, enhancing its opportunity to cause the disease...

OBJECTIVE Combined hyperlipidemia is a common disorder, characterized by a highly atherogenic lipoprotein profile and a substantially increased risk of coronary heart disease. The purpose of this study was to establish whether variations of apolipoprotein A5 (APOA5), a newly discovered gene of lipid metabolism located 30 kbp downstream of the APOA1/C3/A4 gene cluster, contributes to the transmi...

argumentation frameworks [Dun95] take a very simple view on argumentation as they do not presuppose any internal structure of an argument. Abstract argumentation frameworks only consider the interactions of arguments by means of an attack relation between arguments. Definition 1 (Abstract Argumentation Framework). An abstract argumentation framework AF is a tuple AF = (Arg,→) where Arg is a set...