the aim of the present study was to determine the relationship between histopathological lesions and tissue enzymes in chickens affected by marek's disease.five apparently healthy chickens(as control group)and 25 chickens affected by marek's disease were selected. after consideration of history and gross lesions, tissue samples were collected from kidney, liver, heart, ovary, pectoral...

the aim of this study was to investigate the effects of administering antioxidants, including vitamin c and chitosan on oxidative stress markers in muscle as edible tissues of cyprinus carpio exposed to cadmium chloride. in this experiment, by exposing to 0.2 mg/l cadmium chloride for 21 days, fish were fed a normal diet, diet containing chitosan (1000 mg/kg diet), vitamin c (1000 mg/kg diet) o...

objective(s): the aim of the present study is to determine the effect of chloramphenicol (cap) on rat liver and small intestine. effect of phenobarbital (pb) on cap toxicity was also investigated.   materials and methods:   rats were received cap at doses of 0, 200, 400 and 600 mg/kg. another group was pretreated with 80 mg/kg pb 30 min prior to administration of various doses of cap. the exper...

In previous studies, the relationship between aspartate aminotransferase to alanine aminotransferase ratio(AST/ALT ratio) and liver disease has been evaluated. In viral hepatitis, alcoholic liver disease and primary biliary cirrhosis, AST/ALT ratio has been proven to be an indicator of liver cirrhosis.1-3 AST/ALT ratio was a potential value in differentiating nonalcoholic steatohepatitis from a...

Untrained healthy male volunteers were subjected to the study of the effects of physical exercise (bicycle ergometer, 150 W for 30 min) upon the activities of aspartate aminotransferase (AST [GOT]) isoenzymes, soluble and mitochondrial (AST-s and AST-m) with and without reactivation by the co-enzyme pyridoxal 5'phosphate (PALP) in plasma. Blood samples were drawn at the beginning and end of the...

Objective(s): Methylsulfonylmethane (MSM) is a sulfur-containing compound found in a wide range of human foods including fruits, vegetables, grains and beverages. In this study the effect of MSM pretreatment on acetaminophen induced liver damage was investigated. Materials and Methods: Male Sprague Dawley rats were pretreated with 100 mg/kg MSM for one week. On day seven rats were received ace...

Selenium (Se) and many of its compounds are among the most toxic micronutrients. Therefore, determining the optimal level of selenium in the diet of fish is one of the main concerns of researchers. The present study was designed to investigate the effects of Sel-Plex® (Selenium-enriched Saccharomyces cerevisiae yeast) on blood biochemical parameters in juvenile Siberian sturgeon, Acipenser baer...

Abbreviations: NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; NAS, NAFLD activity score; ALT, alanine aminotransferase; GGT, γ-glutamyl transpeptidase; BMI, body mass index; AST, aspartate aminotransferase; CK-18, cytokeratin 18; sFas, soluble Fas; AUC, area under curve Corresponding author: Chang Wook Kim Department of Internal Medicine, Uijeongbu St. Mary’s Hospi...