Baloxavir marboxil is a novel anti-influenza drug with unique mechanism of action that can effectively treat both type A and B influenza. Key intermediate compound 7,8-difluoro-6,11-dihydrodibenz[b,e]thiophene-11-one not only an important component the chemical structure baloxavir but also essential in synthetic route drug. However, conventional synthesis methods for key usually utilize dangero...
