Background and Aims: Diabetes mellitus causes testicular damage by increasing oxidative stress and inflammation. In the present study, modulation of oxidative stress by pioglitazone, a synthetic ligand of peroxisome proliferator-activated receptor-γ, was examined in testis of streptozotocin-induced diabetic rats. Materials and Methods: Diabetes was induced by a single dose of streptozot...

Objective: The purpose of this study was to examine the effects apocynin (APC), an inhibitor NADPH oxidase (NOX), on high-fat diet (HF)-induced testis cytotoxicity. 
 Methods: Wistar albino rats were divided into three groups as control, HF and HF+APC groups. Rats in fed using for 16 weeks last four period vehicle solution or APC (25 mg/kg) administered orally five days a week, respectivel...

Synthetic, structural and biological aspects of tetraazamacrocyclic complexes of Tin(II) have been described. The complexes were characterized by elemental analysis, molecular weight determination conductance measurements and electronic, infrared, H,C and Sn NMR spectral studies. Ligand and their unsymmetrical complexes have been tested for their antimicrobial effects on several pathogenic fung...

This study investigated the protective effects of diallyl disulfide (DADS) against cyclophosphamide (CP)-induced testicular toxicity in male rats. DADS was gavaged to rats once daily for 3 days at 100 mg/kg/day. One hour after the final DADS treatment, the rats were given a single intraperitoneal dose of 150 mg/kg CP. All rats were killed and necropsied on day 56 after CP treatment. Parameters ...

The aim of the study was to compare the arteries supplying human and bovine masculine gonads. The study was made on two extremely different types of location of the mediastinum testis. The study was made on 100 (50 human and 50 bovine) corrosive casts of the testicular, cremasteric, and deference duct arteries. The differences between the species included different courses of the testicular art...

Examination of semen / ejaculates sperm is the first screening examination that a subfertile infertile couple needs to undertake in an attempt find out cause infertility may come from his side. Besides spermanalysis, it also necessary do physical examination, especially about internal and external genital tool because as known abnormal result analysis can be caused by anatomical abnormalities o...

AIM The pathogenesis of hypogonadism in liver cirrhosis is not well understood. Previous results from our laboratory showed that IGF-1 deficiency might play a pathogenetic role in hypogonadism of cirrhosis. The administration of IGF-1 for a short period of time reverted the testicular atrophy associated with advanced experimental cirrhosis. The aim of this study was to establish the historical ...

Cyclin A is a member of the cyclin family of proteins, which are required for both the mitotic and meiotic divisions that characterise spermatogenesis in human and other mammalian species. The data on cyclin A expression in various human spermatogenic disorders and its relationship to the morphology of seminiferous tubules are not well clarified. This study aimed to evaluate the immunohistochem...