Oral azithromycin has been used successfully to treat rosacea, a chronic skin disease that requires long-term therapy. A study was undertaken to determine if C. pneumoniae could play a causative role in acne rosacea. A series of 10 adults presenting with acne rosacea were selected to receive azithromycin alone for the treatment of acne rosacea. C. pneumoniae was detected in cheek biopsy specime...

Introduction. Azithromycin is among the broad-spectrum antibiotics that is widely available in various environmental systems and could have destructive effects on the ecosystem and human health due to its bacterial resistance. In this study, removal of azithromycin from wastewater using an advanced oxidation process of ultraviolet light with and without persulfate was investigated and effective...

This summary of the current knowledge of macrolide therapy serves as an example of recent progress in the therapeutic approach to treating patients with cystic fibrosis (CF). The benefit of macrolides in the treatment of patients with diffuse panbronchiolitis and Pseudomonas aeruginosa infections, as seen in Japan, was the rational behind trials in patients with CF. Thus far, the majority of re...

n engl j med 365;8 nejm.org august 25, 2011 754 However, if azithromycin is going to be used in patients who are known to have frequent exacerbations of COPD, then the local antibiotic resistance patterns should be closely monitored. It also makes sense to ask whether, in such patients, subsequent exacerbations should be treated empirically with a different class of antibiotics. On balance, how...

IMPORTANCE Macrolide antibiotics have been shown beneficial in cystic fibrosis (CF) and diffuse panbronchiolitis, and earlier findings also suggest a benefit in non-CF bronchiectasis. OBJECTIVE To determine the efficacy of macrolide maintenance treatment for adults with non-CF bronchiectasis. DESIGN, SETTING, AND PARTICIPANTS The BAT (Bronchiectasis and Long-term Azithromycin Treatment) stu...

background helicobacter pylori eradication with clarithromycin is more expensive than with azithromycin. objectives this study aimed to compare the effectiveness of these two antibiotics in eradicating h. pylori in hemodialysis (hd) patients. patients and methods this is a prospective, randomized, double-blinded clinical trial analysis of hd patients. patients who had dyspepsia and showed posit...