In our previous works, we have demonstrated that terfenadine (TEF) induces DNA damage and apoptosis in human melanoma cell lines. In this present work, we have studied the effect of histamine on viability of A375 human melanoma cells and the cell-signalling pathways through which TEF may induce its apoptotic effect. We have found that exogenous histamine stimulates A375 melanoma cell proliferat...

The thermic effect of food (TEF) is the well-known concept in spite of its difficulty for measuring. The gold standard for evaluating the TEF is the difference in energy expenditure between fed and fasting states (ΔEE). Alternatively, energy expenditure at 0 activity (EE0) is estimated from the intercept of the linear relationship between energy expenditure and physical activity to eliminate ac...

Ethiopian injera, a soft pancake, baked from fermented batter, is preferentially prepared from tef (Eragrostis tef) flour. The phytic acid (PA) content of tef is high and is only partly degraded during the fermentation step. PA chelates with iron and zinc in the human digestive tract and strongly inhibits their absorption. With the aim to formulate a starter culture that would substantially deg...

Four rations that differed in their crude protein and essential amino-acid content were compiled. Digestibility of the crude protein and essential amino-acid contents were determined biologically in a feeding trial using 4 Anglo-Arab stallions. Their respective daily diets were: Diet 1:2 kg cubes, 5 kg tef hay (Eragrostis tef); Diet 2:2 kg cubes, 5 kg lucerne hay (Medicago sativa); Diet 3:2 kg ...

Anastomotic stricture (AS) and recurrent tracheoesophageal fistula (TEF) are two complications of surgical repair of esophageal atresia (EA). Therapeutic endoscopic modalities include stenting, tissue glue, and clipping for TEF and endoscopic balloon dilation bougienage and stenting for esophageal strictures. We report herein a two-month infant with both EA and TEF who benefited from a surgical...

The low average grain yield (0.7 ton ha(-1)) of tef in Ethiopia is mainly attributed to low soil fertility, and inappropriate tillage and weeds control practices. Despite this, limited scientific information has been documented so far on their interaction effects on tef crop productivity in northern Ethiopia. The objective of this study was to assess the separate and interaction effects of till...

Stob NR, Bell C, van Baak MA, Seals DR. Thermic effect of food and -adrenergic thermogenic responsiveness in habitually exercising and sedentary healthy adult humans. J Appl Physiol 103: 616–622, 2007. First published April 26, 2007; doi:10.1152/japplphysiol.01434.2006.—The thermic effect of food (TEF) is an important physiological determinant of total daily energy expenditure (EE) and energy b...

The views, opinions and/or findings contained in this report are those of The MITRE Corporation and should not be construed as an official Government position, policy, or decision, unless designated by other documentation. Executive Summary Many approaches commonly used to develop a Service-Oriented Environment (SOE) presume the availability of reliable, consistently available networks that pro...

A 26-year-old lady was referred for evaluation of dysphagia. The patient had consumed 50 ml of organophosphorus (OP) components of liquid pesticide 4 months ago and was on ventilatory support with a tracheostomy tube because of OP-poisoning-induced respiratory failure. Treatment included injection of atropine, pralidoxime and other supportive care, and the patient recovered. The patient develop...

The thermic effect of food (TEF), defined as the increase in metabolic rate after ingestion of a meal, has been studied extensively, but its role in body weight regulation is controversial. We analyzed 13 1 TEF tests from a wide range of subjects ingesting meals of varying sizes and compositions. Each test lasted 6 h. Of the total 6-h TEF, 60% of the total had been measured after 3 h, 78% after...