نتایج جستجو برای: tear osmolarity

تعداد نتایج: 13210  

2017
Michelle J Kim Sandra S Stinnett Preeya K Gupta

PURPOSE The goal of this study was to evaluate the effect of thermal pulsation treatment on tear film parameters, specifically osmolarity and matrix metalloproteinase-9 (MMP-9), in patients with meibomian gland dysfunction (MGD) and dry eye disease (DED). METHODS A single-center review of 189 eyes that underwent thermal pulsation treatment was performed. Data were collected on pre and posttre...

Journal: :Cornea 2013
Ali A Abusharha E Ian Pearce

PURPOSE To investigate the effect of exposure to a low relative humidity (RH) environment on tear film physiology. METHOD A controlled environment chamber was used to create 2 different environmental conditions. Ambient temperature was constant in both conditions (21°C) while the RH was set at 40% at the normal condition and at 5% in the desiccating environment. Tear evaporation, noninvasive ...

Journal: :Progress in retinal and eye research 2010
E A Gaffney J M Tiffany N Yokoi A J Bron

Tear hyperosmolarity is thought to play a key role in the mechanism of dry eye, a common symptomatic condition accompanied by visual disturbance, tear film instability, inflammation and damage to the ocular surface. We have constructed a model for the mass and solute balance of the tears, with parameter estimation based on extensive data from the literature which permits the influence of tear e...

Journal: :Investigative ophthalmology & visual science 2011
Jonathan E Moore Gilbert T Vasey Darlene A Dartt Victoria E McGilligan Sarah D Atkinson Claire Grills Philip J Lamey Antonio Leccisotti David G Frazer Tara C B Moore

PURPOSE To investigate the effect of tear hyperosmolarity and signs of clinical ocular surface pathology on conjunctival goblet cell population. METHODS 111 participants were assessed using tear osmolarity (TO) measurements and a comprehensive selection of clinical ophthalmic tests. The resultant clinical database was assessed for evidence of patterns of composite increasing pathology. The to...

Journal: :Journal of Nippon Medical School 2021

2016
Alice T. Epitropoulos Eric D. Donnenfeld Zubin A. Shah Edward J. Holland Michael Gross William J. Faulkner Cynthia Matossian Stephen S. Lane Melissa Toyos Frank A. Bucci Henry D. Perry

PURPOSE To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity, matrix metalloproteinase-9 (MMP-9), tear break-up time (TBUT), Ocular Surface Disease Index (OSDI), fluorescein corneal staining, Schirmer score, meibomian gland dysfunction (MGD) stage and omega-3 index in subjects with dry eyes and confirmed MGD. METHODS This was a multicenter, prospective, interventi...

Journal: :Czech and Slovak Ophthalmology 2018

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