Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) has been shown to induce changes in motor performance and learning. Recent studies indicate that tDCS is capable of modulating widespread neural network properties within the brain. However the temporal evolution of online- and after-effects of tDCS on functional connectivity (FC) within and across the stimulated ...

Most forms of tinnitus are attributable to reorganization and hyperactivity in the auditory central nervous system with coactivation of nonauditory brain structures. One such nonauditory brain area is the dorsolateral prefrontal cortex (DLPFC), which is important for the integration of sensory and emotional aspects of tinnitus. Based on extensive evidence that transcranial direct current stimul...

26 Transcranial oscillatory current stimulation has recently emerged as a non-invasive 27 technique that can interact with ongoing endogenous rhythms of the human brain. 28 Yet, there is still little knowledge on how time-varied exogenous currents acutely 29 modulate cortical excitability. In ten healthy individuals we used online single-pulse 30 transcranial magnetic stimulation (TMS) to searc...

OBJECTIVE Transcranial direct current stimulation (tDCS) has been shown to improve pain symptoms in fibromyalgia (FM), a central pain syndrome whose underlying mechanisms are not well understood. This study was undertaken to explore the neurochemical action of tDCS in the brain of patients with FM, using proton magnetic resonance spectroscopy (1H-MRS). METHODS Twelve patients with FM underwen...

obesity is a chronic, multifactorial disease. there are a number of neurocognitive and behavioral mechanisms that contribute to overeating, or eating past nutritional needs, which can lead to obesity. obese people suffer from attention bias to food-related cues. we have different methods to modify attentional biases, such as transcranial direct current stimulation (tdcs) and attention modificat...

Transcranial Direct Current Stimulation (tDCS) is investigated for a broad range of neuropsychiatric indications, various rehabilitation applications, and to modulate cognitive performance in diverse tasks. Specificity of tDCS refers broadly to the ability of tDCS to produce precise, as opposed to diffuse, changes in brain function. Practically, specificity of tDCS implies application-specific ...

Background: Remifentanil-induced hyperalgesia (r-IH) involves an imbalance in the inhibitory and excitatory systems. As the transcranial Direct Current Stimulation (tDCS) modulates the thalamocortical synapses in a top-down manner, we hypothesized that the active (a)-t-DCS would be more effective than sham(s)-tDCS to prevent r-IH. We used an experimental paradigm to induce temporal summation of...

PURPOSE Weak direct currents induce lasting alterations of cortical excitability in animals and humans, which are controlled by polarity, duration of stimulation, and current strength applied. To evaluate its anticonvulsant potential, transcranial direct current stimulation (tDCS) was tested in a modified cortical ramp-stimulation model of focal epilepsy. METHODS The threshold for localized s...

Transcranial direct current stimulation (tDCS) has been used to modify motor performance in healthy and patient populations. However, our understanding of the large-scale neuroplastic changes that support such behavioural effects is limited. Here, we used both seed-based and independent component analyses (ICA) approaches to probe tDCS-induced modifications in resting state activity with the ai...

Transcranial DC stimulation (tDCS) induces stimulation polarity-dependent neuroplastic excitability shifts in the human brain. Because it accomplishes long-lasting effects and its application is simple, it is used increasingly. However, one drawback is its low focality, caused by 1) the large stimulation electrode and 2) the functionally effective reference electrode, which is also situated on ...