نتایج جستجو برای: tcr
تعداد نتایج: 12834 فیلتر نتایج به سال:
Recently, <span>Telugu character recognition (TCR) becomes a hot research topic because of drastic increase in technological advancements such as multimedia, and smartphones. Though numerous works have been concentrated on offline TCR models, it is still needed to develop automated intelligent online models. This paper presents novel puzzle optimization algorithm with capsule networks-bas...
The CDR3 regions of T cell receptor (TCR)-alpha and -beta chains play central roles in the recognition of antigen (Ag)-MHC complex. TCR repertoire is created on the basis of Ag recognition specificity by CDR3s. To analyze the potential spectrum of TCR-alpha and -beta to exhibit Ag specificity and generate TCR repertoire, we established hundreds of TCR transfectants bearing a single TCR-alpha or...
The stoichiometry of the subunits that comprise the T cell antigen receptor (TCR) complex is not completely known. In particular, it is uncertain whether TCR alpha and TCR beta proteins are present in the TCR complex as one or multiple heterodimeric pairs. In this study we have used mice transgenic for two different TCR alpha and two different TCR beta proteins to determine the number of TCR al...
background: celiac disease (cd) is a small bowel enteropathy caused by permanent wheat gluten intolerance. one of the earliest signs of the mucosal immune activation in cd is an increase in the intestinal intraepithelial lymphocytes (iiels) count in the small intestinal epithelium. although most of those iiels express ??tcr, cd is characterized by an increase in the gdtcr + iiels. objective: th...
T cell receptor (TCR) and variable region genes are assembled from germ-line gene segments located in a single chromosomal locus in which TCR segments are situated between TCR segments. The TCR enhancer (E ) located at the 3 end of the TCR locus functions over a long chromosomal distance to promote TCR rearrangement and maximal TCR expression; whereas the TCR enhancer (E ) is located among the ...
زمینه و هدف: رفلکس تریژمینوکاردیاک (trigeminocardiac reflex, tcr) شامل برادی کاردی، کاهش فشارخون، آپنه و افزایش حرکات معده می باشد که به هنگام دستکاری عصب پنج می تواند بروز کند.معرفی بیمار: بیمار مرد 26 ساله ای بود که با علایم سردرد مداوم یک طرفه، مشکل در بلع مراجعه نموده بود هم چنین کاهش شنوایی عصبی و انحراف زبان به سمت چپ داشت. هنگامی که جراح در حال دایسکشن در مسیر عصب تری ژمینال بود، ناگهان ...
The development of pre-T cells with productive TCR-beta rearrangements can be mediated by each the pre-T cell receptor (pre-TCR), the TCR-alphabeta as well as the TCR-gammadelta, albeit by distinct mechanisms. Although the TCR-gammadelta affects CD4-8- precursor cells irrespective of their rearrangement status by TCR-beta mechanisms not involving TCR-beta selection, both the pre-TCR and the TCR...
Peripheral T lymphocytes each express surface T cell receptor (TCR) alpha and beta chains of a single specificity. These are produced after random somatic rearrangements in TCR alpha and beta germline genes. Published model systems using mice expressing TCR alpha and/or beta chain transgenes have shown that allelic exclusion occurs conventionally for TCR-beta. TCR alpha chain expression, howeve...
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