This chapter discusses estimation, specification testing, and model selection of predictive density models. In particular, predictive density estimation is briefly discussed, and a variety of different specification and model evaluation tests due to various authors including Christoffersen and Diebold (2000), Diebold, Gunther and Tay (1998), Diebold, Hahn and Tay (1999), White (2000), Bai (2003...

Carrier screening programs have historically been focused within a particular group---e.g., Tay-Sachs among Ashkenazic Jews and sickle cell anemia among African Americans. With cystic fibrosis (CF), the potential target population is larger and less defined, which may introduce both technical and organizational complexity not present in past carrier screening. This appendix describes past carri...

Prediction of nontrivial band topology and superconductivity in Mg2Pb Guang Bian,1,* Tay-Rong Chang,2 Angus Huang,3 Yuwei Li,1 Horng-Tay Jeng,3,4,† David J. Singh,1 Robert J. Cava,5 and Weiwei Xie6,‡ 1Department of Physics and Astronomy, University of Missouri, Columbia, Missouri 65211, USA 2Department of Physics, National Cheng Kung University, Tainan 701, Taiwan 3Department of Physics, Nation...

In serum there are two classes of hexosaminidase. One of these is heat-labile and is inactive in children with Tay-Sachs disease. Serum from heterozygotes for Tay-Sachs disease has half the normal activity of the heat-labile enzyme. The heat-labile enzyme can be inactivated by heating serum diluted in buffer for 5 mm at 60 #{176}C. We have used this property to develop a reliable, fully automat...

This study reports for the first time molecular detection of Anaplasma platys infection in 4 (13.3%) of 30 Malaysian dogs investigated. A low occurrence (3.3%) of Babesia gibsoni was also noted, being detected in one of the 30 dogs. Rickettsia, Bartonella, Orientia tsutsugamushi, and Ehrlichia DNA were not detected in the dog blood samples. The role of A. platys as an agent of canine anaplasmos...

BACKGROUND Introduction: GM2 is a type of ganglioside. It is associated with GM2 gangliosidoses such as Tay-Sachs disease.