Radiation oncology is a medical discipline mainly involved in the treatment of cancer with ionizing radiation. It is based on full knowledge of individual patient cancer disease, delineation of the target volume including tumor that has to receive therapeutic radiation dose, delineation of normal tissues to be spared, treatment planning with dedicated calculation algorithms, radiation delivery ...

background: for the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, mrsi was used as a molecular imaging modality with mri and ct images. materials and methods: the images of 20 prostate cancer patients were used in this study. the mr and mrsi images were registered with ct ones using non-rigid registration technique. the ct based planning (bp), ct/mr...

PURPOSE The observation that human meningioma cells strongly express somatostatin receptor (SSTR 2) was the rationale to analyze retrospectively in how far DOTATOC PET/CT is helpful to improve target volume delineation for intensity modulated radiotherapy (IMRT). PATIENTS AND METHODS In 26 consecutive patients with preferentially skull base meningioma, diagnostic magnetic resonance imaging (M...

The delineation of the target volume, i.e. the volume which should be irradiated with a therapeutic dose of irradiation, is of utmost importance in radiotherapy. Modern imaging techniques cannot be missed in this process. Diagnosticians and radiation oncologists therefore should understand each other's needs and potential.

In radiation therapy planning, uncertainties in target volume definition yield a risk of underdosing the tumor. The classical way to prevent this in the context of external beam radiotherapy (EBRT) has been to expand the clinical target volume (CTV) with an isotropic margin to obtain the planning target volume (PTV). However, the EBRT-based PTV concept is not directly applicable to brachytherap...

With great interest we read ‘ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer’ by Offersen et al. [1]. We wish to congratulate the authors their excellent work describing easily applicable, comprehensive guidelines.

Radiotherapy plays an important role in the treatment of rectal cancer. Three-dimensional conformal radiotherapy and intensity-modulated radiotherapy are mainstay techniques of radiotherapy for rectal cancer. However, the success of these techniques is heavily reliant on accurate target delineation and treatment planning. Computed tomography simulation is a cornerstone of rectal cancer radiothe...