نتایج جستجو برای: tangeretin

تعداد نتایج: 122  

Journal: :JNCI Journal of the National Cancer Institute 1999

Journal: :Nutrition and cancer 2008
Edward G Miller Jason J Peacock T Campbell Bourland Samuel E Taylor John M Wright Bhimanagouda S Patil Edward G Miller

Six citrus flavonoids were tested for antineoplastic activity. The hamster cheek pouch model was utilized, and the solutions of the flavonoids (2.0-2.5%) and the solution of the carcinogen, 7,12-dimethylbenz[a]anthracene (0.5%), were applied topically to the pouches. The pouches of the positive controls were treated with the solvent used to dissolve the flavonoids and the solution of the carcin...

2010
Yukihiro Asami Ryo Horie Hiroshi Hamamoto Kazuhisa Sekimizu

BACKGROUND We use silkworms to evaluate therapeutic effects of drug candidates. Our previous reports have revealed that there are common mechanisms of pharmacokinetics of chemicals in silkworms and mammals. In this report, we attempt to establish a method by using silkworms to identify chemicals from plant extracts which are absorbed from intestine and also stably exist in body fluids. RESULT...

2017
Satoshi Okuyama Kohei Miyazaki Rie Yamada Yoshiaki Amakura Morio Yoshimura Atsushi Sawamoto Mitsunari Nakajima Yoshiko Furukawa

Accumulating data have indicated that citrus polymethoxyflavones (PMFs) have the ability to affect brain function. In the present study, we showed that 3,5,6,7,8,3',4'-heptamethoxy- flavone (HMF) given intraperitoneally to mice was immediately detected in the brain and that the permeability of the brain tissues to it was significantly higher than that of other citrus PMFs (nobiletin, tangeretin...

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