a quantitative analysis method for fudosteine in human serum by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry (hplc-esi/ms/ms) was established, which shows high sensitivity and selectivity. the mobile phase composition was 75% 20 mm acetic acid and 25% acetonitril, which was pumped at a flow rate of 0.40 ml/min. the overall chromatographic run time was ...

an open-label, single-dose, randomized, 2-way crossover study was conducted in fasted healthy iranian male volunteers. eligible participants randomly assigned in a 1:1 ratio to be given one tablet of the test or reference formulation, followed by a 2-week washout period and administration of the exchange formulation. a quick and susceptible liquid chromatography–tandem mass spectrometry (lc-ms)...