It has been demonstrated that through the formation of embryoid bodies (EBs) germ cells can be derived from embryonic stem (ES) cells. Here, we describe a transgene expression approach to derive germ cells directly from ES cells in vitro without EB formation. Through the ectopic expression of Deleted in Azoospermia-Like (Dazl), a germ cell-specific RNA-binding protein, both motile tailed-sperm ...

Background: Radiation-induced molecular changes on the endothelial surface of brain arteriovenous malformations (AVM) may be used as markers for specific vascular targeting agents. In this study, we examined the level of expression of platelet endothelial cell adhesion molecule-1 (PECAM-1) on brain endothelial cell surface after radiation treatment, with the aim of targeting the radiation-induc...

the effect of daily oral administration of ephedrine (0, 1, 2, 4 or 8 mg kg-1 w0.75) on carcasscharacteristics of forty-four 2 yr old crossbred (mehraban x ghezel) fat-tailed ewes was studied. theewes were fed a fattening ration, and received ephedrine by using a drenching gun for either 50 or 70days. there was a significant interaction (p

From a rare events perspective, scheduling disciplines that work well under light (exponential) tailed workload distributions do not perform well under heavy (power) tailed workload distributions, and vice-versa, leading to fundamental problems in designing schedulers that are robust to distributional assumptions on the job sizes. This paper shows how to exploit partial workload information (sy...

the objective of the present study was to evaluate the effects of inbreeding on average daily gains and kleiber ratios in moghani sheep. traits included average daily gain from birth to 3 months (adg1), average daily gain from birth to 6 months (adg2), average daily gain from 3 months to 6 months (adg3), average daily gain from 3 months to 9 months (adg4), average daily gain from 3 months to ye...

background: the acute phase response is beneficial to theanimal in restoring homeostasis, and measuring the circulatingacute phase proteins, cytokines, and enzymes can be used toevaluate the innate immune system's responses to invader agentssuch as bacterial lipopolysaccharide. measurement of theseparameters has shown to be useful as diagnostic and prognosticmarkers in animal endotoxemia. objec...

Examination of the recent literature on the question of when to use one-tailed tests of significance in psychological research reveals a state of unresolved disagreement. A variety of differing opinions (1, 2, 5, 7, 8, 9, 10, pp. 62-63) have been presented, ranging from Burke's (2) exhortation that psychologists should never report one-tailed tests in the public literature to Jones' (8) stateme...

The Great-tailed Grackle (Quiscalus mexicanus) and Boat-tailed Grackle (Q. major) are sister species that have expanded their ranges during historical times. This expansion has created an area of sympatry between these species in Texas and Louisiana, and between distinctive Great-tailed Grackle subspecies in the southwestern United States and northern Mexico. We investigated the evolutionary hi...

Cattle persistently infected (PI) with bovine viral diarrhea virus (BVDV), a pestivirus in the family Flaviviridae, are an important source of viral transmission to susceptible hosts. Persistent BVDV infections have been identified in white-tailed deer (Odocoileus virginianus), the most abundant free-ranging ruminant in North America. As PI deer shed BVDV similarly to PI cattle, maintenance of ...

We consider a queue fed by a mixture of light-tailed and heavytailed traffic. The two traffic classes are served in accordance with the Generalized Processor Sharing (GPS) discipline. GPS-based scheduling algorithms, such as Weighted Fair Queueing (WFQ), have emerged as an important mechanism for achieving service differentiation in integrated networks. We derive the asymptotic workload behavio...