It has been demonstrated that okadaic acid-insensitive protein phosphatases are involved in dephosphorylation of autophosphorylated Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) in rat cerebellar granule cells (Fukunaga, K., Rich, D. P., and Soderling, T. R. (1989) J. Biol. Chem. 264, 21830-21836). In the present study, recombinant rat protein phosphatase 2C (PrP-2C) expressed in ...

Cell migration and invasion are key processes in the metastasis of cancer, and suppression of these steps is a promising strategy for cancer therapeutics. The aim of this study was to explore small molecules for treating colorectal cancer (CRC) and to investigate their anti-metastatic mechanisms. In this study, six CRC cell lines were used. We showed that YH-306 significantly inhibited the migr...

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http://www.sciencemag.org/cgi/content/full/293/5528/306 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/293/5528/306/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...

http://www.sciencemag.org/cgi/content/full/306/5697/865 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/306/5697/865/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...

CHEMIN, A COMBINED XRD/XRF INSTRUMENT. S. J. Chipera, D. T. Vaniman, D. L. Bish, P. Sarrazin, S. Feldman, D. F. Blake, G. Bearman, and Y. Bar-Cohen, Los Alamos National Laboratory, MS D469, Los Alamos, NM 87545, Indiana University, 1001 E 10th St., Bloomington, IN 47405, Apparati Inc., 110 Pioneer Way, Suite I, Mountain View, CA 94041, NASA Ames Research Center, MS 239-4, Moffett Field, CA 9403...

1 Casas J A, Subauste C P, Alarc6n G S. A new promising treatment in systemic sclerosis: 5-fluorouracil. Ann Rheum Dis 1987; 46: 763-7. 2 Calabresi P, Parks R E Jr. Chemotherapy of neoplastic diseases. In: Gilman A G, Goodman L S, Rall T W, Murad F, eds. Goodman and Gilman's the pharmacological basis of therapeutics. 7th ed. New York: Macmillan, 1985: 1240-306. 3 Physicians' Desk Reference (PDR...

944. Preparative and structural studies on sulfur-linked carborane icosahedra: 2-phenyl-ortho-carboranylsulfur systems (2-Ph-1, 2-C2B10H10)2X (X = S, S2 or SO), and ortho-carboran-di-yl systems (1, 2-C2H10H10Y)2 (Y = S or SO) A. S. Batsanov, W. Clegg, R. C. B. Copley, M. A. Fox, W. R. Gill, R. S. Grimditch, T. G. Hibbert, J. A. K. Howard, J. A. H. MacBride and K. Wade. Polyhedron 2006, 25, 300–...