The occurrence of additional cardiovascular events when the diastolic blood pressure is lowered below a critical level is referred to as "the diastolic J curve." Although the critical level of diastolic blood pressure where the J curve begins is not certain, increasingly strong evidence from prospective, controlled studies has confirmed the existence of such a J curve. With the likely addition ...

BACKGROUND Isolated systolic hypertension is an important risk factor for cardiovascular events. The purpose of this study was to detect the prevalence of and to evaluate the effectiveness of currently available medications in the treatment of uncontrolled isolated systolic hypertension. METHODS We randomly selected a total of 585 patients with hypertension from our database. The two most rec...

Until the 1980’s the diastolic blood pressure (DBP) was assumed to be the most relevant hemodynamic parameter for prognosis of hypertensive patients. Elevated systolic pressure was considered as an inevitable consequence of aging and many physicians were reluctant to pay credence to the need for therapy of elevated systolic blood pressure. There was a radical change in thinking based on epidemi...

BACKGROUND AND PURPOSE Despite clear evidence that blood pressure (BP) lowering is effective for prevention of cardiovascular events among patients with isolated systolic hypertension and systolic-diastolic hypertension, there is ongoing uncertainty about its effects in those with isolated diastolic hypertension. The objective of the present analysis is to determine whether BP lowering provides...

Objective: Hypertension is a major risk factor for stroke, renal failure, and heart failure globally. This trend of complications has been seen even among our rural and urban dwellers in the tropics. This study aims at determining the prevalence and pattern of hypertension and body mass index (BMI) in six rural communities in Southern Nigeria.Methods: Adult participants, aged 18-80 years ...

OBJECTIVE To delineate more precisely an operational threshold for making clinical decisions based on ambulatory blood pressure (ABP) measurement by studying the ABP in subjects who were diagnosed as either normotensive or hypertensive by conventional blood pressure (CBP) measurement. SUBJECTS Twenty-four research groups recruited 7069 subjects. Of these, 4577 were normotensive (systolic CBP ...