A cationic cyclopentannelation reaction has afforded a very simple route to a wide variety of methylenomycin analogs. The antibacterial activity of these readily accessible synthetic compounds parallels that of naturally occurring methylenomycin A. The in vitro antitumor activity of the synthetics assayed using human nasopharyngeal carcinoma (KB) cells is particularly promising.

Table 1. Types of materials used in pelvic organ prolapse repair (5,7,8,9). A. Biologics: 1Autologous fascia: Rectus fascia, fascia lata, vaginal mucosa, skin graft 2Heterologous: i) Allogenic: CadavaericDura matter, Rectus sheath, Fascia lata, Dermis, ii) Xenogenic: Porcine dermis, small intestine submucosa, bovine pericardium, fetal bovine dermis. B. Synthetics: 1Absorbable: Polyglycolic acid...

Since Tuffier's original description of the extrapleural operation in 1891, the procedure has been subjected to various modifications, particularly the introduction of different plombage materials. Fat was probably the first solid plombe to be employed, but was discarded rather early because of its inherent deficiencies: lack of resistance to pressure and tendency to liquefy. Bear's introductio...

on foreign sources, chiefly Germany, for the supply of almost all her requirements in this direction. This was strikingly manifested by the precipitous rise in prices immediately after the declaration of war against Germany in 1939. Since then the shortage of German-made and other imported synthetics has caused two important results : (1) Indian physicians are gradually showing an increasing co...