background: nowadays, there's a growing demand for the natural antioxidants due to the harmful effects of synthetic antioxidants. therefore, introduction of new natural antioxidants (especially those with plant origin) is very important. objective: the present study explores the chemical constitution and antioxidant activity of leaf extract of hyssopus officinalis l. and extract of aerial ...

A few facile synthetic pathways for bicyclic aminopyridinol antioxidants are presented. Attachment of a long alkyl chain to the bicyclic pyridinol scaffold was established using ester linkage. Non-substituted pyrrolopyridinols and 1,3-oxazine-fused pyridinols were also synthesized as novel antioxidant scaffolds. Antioxidant activities were measured by a radical clock method and new compounds pr...

The purpose of this study was to evaluate and compare the free-radical scavenging activity against DPPH stable radical and protective properties of the natural products SQGD and P. corylifolia and synthetic nitroxylfree radical containing nitrosoureas SLENU and SLCNUgly against in vivo oxidative toxicity of antitumor drug CCNU. It was found statistically significant increase in the DPPH radical...

A simple and efficient method was established for the determination of synthetic antioxidants in beverages by using dispersive liquid-liquid microextraction combined with high-performance liquid chromatography with ultraviolet detection. Butylated hydroxy toluene, butylated hydroxy anisole, and tert-butylhydroquinone were the antioxidants evaluated. Experimental parameters including extraction ...

Synthetic water-soluble phenolic antioxidants are known anti-inflammatory chemicals, some of them were shown to induce components of antioxidative defense enzymes NADPH:quinone oxidoreductase (NQO1) and glutathione-S-transferase (GST) via activation of Nrf2 pathway. Our experimental in vivo models have demonstrated an increase of both gstp1 and nqo1 expression in the liver of mice treated with ...

compounds derived from lipid oxidation endangering human health and lead to cardiovascular disease and cancer. the addition of antioxidants is effective in retarding the oxidation of lipids and lipid containing foods. due to the toxicological effects of synthetic antioxidants, decrease their use and replacing them with natural antioxidants. this study investigates antioxidant effect of pimpinel...

      Butyl-hydroxytoluene (BHT) is one of the major synthetic antioxidants with a wide range usage. Replacement of artificial antioxidants with natural antioxidants is highly considered. In this research, the antioxidant activity of Juniperus excelsa was investigated by using reducing power, DPPH radical scavenging and inhibition of lipid peroxidation. Also, the amounts of phenolic an...