Staining the entire chain of paravertebral sympathetic ganglia in the bullfrog with an antiserum against porcine neuropeptide Y (NPY) revealed that, in each ganglion, a subpopulation of neurons expresses NPY-like immunoreactivity. Chromaffin cells in the sympathetic ganglia and in the adrenal gland were not stained by the anti-NPY serum. Since neurons in ganglia 9 and 10 of the sympathetic chai...

Sympathetic axons invade the trigeminal ganglia of mice overexpressing nerve growth factor (NGF) (NGF/p75(+/+) mice) and surround sensory neurons having intense NGF immunolabeling; the growth of these axons appears to be directional and specific (). In this investigation, we provide new insight into the neurochemical features and receptor requirements of this sympathosensory sprouting. Using do...

BACKGROUND Sprouting of sympathetic fibers into sensory ganglia occurs in many preclinical pain models, providing a possible anatomical substrate for sympathetically enhanced pain. However, the functional consequences of this sprouting have been controversial. We used a transgenic mouse in which sympathetic fibers expressed green fluorescent protein, observable in live tissue. Medium and large ...

as the sympathetic neurohormone has evolved fronm much impressive circumistantial evidence; however, it has not been demonstrated that the biosynthesis of norepinephrine takes place in the sympathetic nerves and ganglia. This paper shows, through the use of labeled precursors, that the sympathetic nerves and ganglia synthesize norepinephrine in a systematic sequence from tyrosine and that this ...

The Cardiac Arrhythmia Suppression Trial demonstrated that antiarrhythmic drugs not only fail to prevent sudden cardiac death, but actually increase overall mortality. These findings have been confirmed in additional trials. The "proarrhythmic" effects of most currently available antiarrhythmic drugs makes it essential that we investigate novel strategies for the prevention of sudden cardiac de...

The celiac ganglia and the visceral plexus are complexes structures, disposed in the proximity of the main collateral branches of the aorta. Pre visceral ganglia are sympathetic ganglia chains between the lateral vertebral sympathetic chain and viscera. Our study is made in the anatomy lab on 30 adult human bodies, one of new born and 10 human fetal specimens with crown-rump lengths from 9 to 2...

The autonomic nervous system of the chimaeroid fish Hydrolagus colliei has been investigated by dissections and histological methods. It consists of a cranial parasympathetic portion and a sympathetic portion confined to the trunk. The latter extends from the level of the heart to the anus and consists of segmentally arranged ganglia on each side of the dorsal aorta. These ganglia are closely a...

Sympathetic ganglia consist of noradrenergic and cholinergic neurons. The cholinergic marker protein vesicular acetylcholine transporter (VAChT) and the neuropeptide vasoactive intestinal peptide (VIP), co-expressed in mature cholinergic sympathetic neurons, are ®rst detectable during embryonic development of rat sympathetic ganglia. However, the subpopulation of cholinergic sympathetic neurons...

H2S is well-known as hypotensive agent, whether it is synthetized endogenously or administered systemically. Moreover, the H2S donor NaHS has been shown to inhibit vasopressor responses triggered by stimulation of preganglionic sympathetic fibers. In contradiction with this latter result, NaHS has been reported to facilitate transmission within sympathetic ganglia. To resolve this inconsistency...

The vasospastic diseases and chronic pain related to lower limb have been successfully treated by surgical ablation of lumbar sympathetic trunk for last 80 years.Precise knowledge of anatomy of lumbar sympathetic trunk and its adjoining structures is mandatory for safe and uncomplicated lumbar and spinal surgeries.We aim to study the detailed anatomy of entry and exit of lumbar sympathetic trun...