Abstract Remove unwanted variation (RUV) is an estimation and normalization system in which the underlying correlation structure of a multivariate dataset estimated from negative control measurements, typically gene expression values, are assumed to stay constant across experimental conditions. In this paper we derive weight matrix incorporated into generalized least squares estimates RUV‐inver...

We present a novel data organization for disk arrays|Segmented Information Dispersal (SID). SID provides protection against disk failures while ensuring that the reconstruction of the missing data requires only relatively small contiguous accesses to the available disks. SID has a number of properties that make it an attractive solution for fault-tolerant video servers. Under fault-free conditi...

It has been shown that for k = 8 or 9, there exists a BIBD(v, k, 1) for all positive integers v == 1 or k (mod k(k-1)), with some possible exceptions. We show that such designs exist for 49 of these exceptional values. A balanced incomplete block design (BIBD) with parameters (v, k, 1) is a pair (X, A) where X is a v-set and A is a family of k-subsets (where 2 < k < v) called blocks, such that ...

For asynchronous Wireless Sensor Networks (WSNs), this research suggests an ideal Balanced Incomplete Block Design (BIBD) extended design based neighbour finding technique. The algorithm takes use of the characteristics BIBD designs to build a series transmission plans that guarantee effective detection with little energy consumption and delay. Simulations are used test proposed algorithm, resu...

A pairwise balanced design is an ordered pair S,B , denoted PBD S,B , where S is a finite set of symbols, and B is a collection of subsets of S called blocks, such that each pair of distinct elements of S occurs together in exactly one block of B. Here |S| v is called the order of the PBD. Note that there is no condition on the size of the blocks in B. If all blocks are of the same size k, then...

Choreoathetoid involuntary movements are rarely reported in patients with frontotemporal lobar degeneration (FTLD), suggesting their exclusion as a supportive feature in clinical diagnostic criteria for FTLD. Here, we identified three cases of the behavioral variant of frontotemporal dementia (bvFTD) that display chorea with fused in sarcoma (FUS)-positive inclusions (FTLD-FUS) and the basophil...

Immunoglobulins (Igs), the key effectors of the adaptive immune system, mediate the specific recognition of foreign structures, i.e. antigens. In mammals, IgM production commonly precedes the production of IgG in the response to an infection. The reptilian counterpart of IgG is IgY, but the exact kinetics of the reptilian immune response are less well known. Boid inclusion body disease (BIBD), ...

Optical code division multiple access (OCDMA) shows limitations in terms of the inefficient bandwidth utilization and low spectral density with one-dimensional (1D) codes. To overcome these limitations, a novel design is presented using two dimensional (2D) spectral/spatial multiwavelength coding scheme. The proposed constructed 1D balanced incomplete block (BIBD) technique. Theoretical analyti...

In this article, we consider the construction of generalized group divisible designs with two groups (GGDD (2)) from balanced incomplete block designs (BIBD). We also discuss MV-optimality of these designs.