BACKGROUND Left ventricular assist device (LVAD) has become an alternative treatment for end-stage heart failure patients. Series type of LVAD, as a novel LVAD, has attracted more and more attention. The hemodynamic effects of series type LVAD on aortic blood pattern are considered as its important characteristics; however, the precise mechanism of it is still unclear. METHODS To clarify the ...

This thesis is motivated by the necessity to understand the flow structure of turbulent flows in bends encountered in many technical applications such as heat exchangers, nuclear reactors and internal combustion engines. Flows in bends are characterised by strong secondary motions in terms of counter-rotating vortices (Dean cells) set up by a centrifugal instability. Specifically the thesis dea...

BACKGROUND AND OBJECTIVES Storage lesions may prevent transfused platelets to respond to agonists and arrest bleeding. The aim of this study was to evaluate and quantify the capacity of platelet activation during storage using flow cytometry and new markers of platelet activation. MATERIALS AND METHODS Activation responses of platelets prepared by apheresis were measured on days 1, 5, 7 and 1...

PURPOSE To test our hypothesis about whether there is water migration in the horizontal corneal plane and investigate its developmental mechanism. METHODS A fluorescein solution was intrastromally injected into normal and edematous corneas of rabbits, and the movement of the fluorescein solution was observed and recorded over time. RESULTS In normal corneas, the water flow was characterized...

A comparative performance analysis of the CFD platforms OpenFOAM and FLOW-3D is presented, focusing on a 3D swirling turbulent flow: a steady hydraulic jump at low Reynolds number. Turbulence is treated using RANS approach RNG k-ε. A Volume Of Fluid (VOF) method is used to track the airewater interface, consequently aeration is modeled using an EulerianeEulerian approach. Structured meshes of c...

A high-speed gas flow, generated by a miniature supersonic nozzle for microparticle acceleration, is investigated. In medical application, the powder formulation of drugs can be delivered into human skin or mucosal tissue for the treatment of a range of diseases. One of the main concerns for designing and evaluating such system is ensuing that microparticles are delivered into human skin with a...