Proteus mirabilis rapidly migrates across surfaces using a periodic developmental process of differentiation alternating between short swimmer cells and elongated hyperflagellated swarmer cells. To undergo this vigorous flagellum-mediated motility, bacteria must generate a substantial proton gradient across their cytoplasmic membranes by using available energy pathways. We sought to identify th...

Pseudomonas aeruginosa is known to produce surfactants that are involved in its swarming motility behavior, such as rhamnolipids and their precursors-3-(3-hydroxyalkanoyloxy)-alkanoic acids (HAAs). In P. aeruginosa PAO1, swarming motility is inhibited by some fatty acids, including branched-chain fatty acids and unsaturated fatty acids. In the present study, addition of 12-methyltetradecano...

We present a cell-based model to simulate the swarming behavior of various mutants of myxobacteria. Computational complexity is often known to be one of the biggest obstacles in simulating such biological system as there are too many interacting individuals involved in the system. We derive the scaling law for our model, which together with the concept of superindividuals, enable us to perform ...

Most multi-agent systems are inspired by classical AI, whose objective was to realize humanlevel intelligence in a computer. As the field has moved toward multiple agents, there has been a presumption that individual agents still aspire to high-level intelligence. Swarming systems follow an alternative model, inspired more by artificial life than artificial intelligence. The individual agents i...

While techniques exist for simulating swarming behaviors, these methods usually provide only simplistic navigation and planning capabilities. In this review, we explore the benefits of integrating roadmap-based path planning methods with flocking techniques to achieve different behaviors. We show how group behaviors such as exploring can be facilitated by using dynamic roadmaps (e.g., modifying...

Swarming motility is suggested to be a social phenomenon that enables groups of bacteria to coordinately and rapidly move atop solid surfaces. This multicellular behavior, during which the apparently organized bacterial populations are embedded in an extracellular slime layer, has previously been linked with biofilm formation and virulence. Many population density-controlled activities involve ...

During late summer and early autumn in temperate zones of the Northern Hemisphere, thousands of bats gather at caves, mainly for the purpose of mating. We demonstrated that this swarming behavior most probably leads not only to breeding among bats of the same species but also interbreeding between different species. Using 14 nuclear microsatellites and three different methods (the Bayesian assi...

Bacteria can coordinate several multicellular behaviors in response to environmental changes. Among these, swarming and biofilm formation have attracted significant attention for their correlation with bacterial pathogenicity. However, little is known about when and where the signaling occurs to trigger either swarming or biofilm formation. We have previously identified an RssAB two-component s...