BACKGROUND Levetiracetam is widely used as adjunctive therapy in the treatment of partial-onset seizures, myoclonic seizures, primary generalized tonic-clonic seizures, and idiopathic generalized epilepsy in the community and in hospital. However, no convenient, easy-to-swallow dosage form is commercially available in Canada. Moreover, no stability data are available for this antiepileptic prep...

Production of exopolysaccharides (EPSs) has been reported in prokaryotes and eukaryotes. Microbial have increased interest as another category microbial products utilized the pharmaceutical, biomedical, food industries. Investigators are considering replacing synthetic stabilizers with organic ones by investigating EPS fermentation-based dairy Particularly for enhancement rheology fermented ite...

Deliberation over and management of goals is a key aspect of an agent’s architecture. We consider the various types of goals studied in the literature, including performance, achievement, and maintenance goals. Focusing on BDI agents, we develop a detailed description of goal states (such as whether goals have been suspended or not) and a comprehensive suite of operations that may be applied to...

Objective: The aim of the present study was to develop and evaluate the monolithic osmotic tablet (MOT) composed of the solid dispersion of ketoprofen (KETO), a poorly water-soluble drug. Solid dispersion technique is generally used for immediate release, as this maximizes the amount of drug absorbed. Sustained release may be obtained by combining solid dispersion technique with MOT so as to in...

This chapter presents an agent-based architecture for integrating organizational knowledge repositories and business processes orchestrated by a workflow management system. This architecture proactively provides relevant knowledge to workflow tasks considering their context, and stores the information generated by its execution for future requirements. It describes components of the architectur...

Croscarmellose sodium is a very commonly used pharmaceutical additive approved by the US Food and Drug Administration. It is used in injectable preparations as a suspending agent to promote solubilization of compounds with poor water solubility; it is also present in tablets as binder, glidant and antiadherent, in bulk laxatives as active principle and as an additive in food products. Croscarme...

In their everyday lives people flexibly handle many tasks. They work on one at a time, make quick decisions about which one to work on, and put aside tasks whenever attending to them is not required to achieve the task’s goal. This last capability is critical because rather than fixate on a blocked task, a person can work on some other task. For example, a person making bean soup wouldn’t watch...