Susac syndrome is a rare disease of unknown pathogenesis. It is caused by a microangiopathy affecting the arterioles of the brain, retina, and cochlea, giving the classic clinical triad of subacute encephalopathy, visual loss secondary to retinal branch occlusions, and sensorineural hearing loss. The features of four cases of this syndrome are presented. MR imaging, retinal fluorescein angiogra...

BACKGROUND AND PURPOSE Susac syndrome is a rare disorder consisting of encephalopathy, hearing loss, and retinal arteriolar occlusions. The purpose of this study was to evaluate the evolution of lesions in this disease by using serial MR imaging with diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADCs). Abnormalities in the nonlesional white matter (NLWM) were also analyz...