نتایج جستجو برای: suppressive therapy
تعداد نتایج: 665551 فیلتر نتایج به سال:
Although discontinuation of suppressive antifungal therapy for acquired immunodeficiency syndrome (AIDS)-associated histoplasmosis is accepted for patients with immunologic recovery, there have been no published studies of this approach in clinical practice, and minimal characterization of individuals who relapse with this disease. We performed a multicenter retrospective cohort study to determ...
CONTEXT Reduction of gastric acid secretion by acid-suppressive therapy allows pathogen colonization from the upper gastrointestinal tract. The bacteria and viruses in the contaminated stomach have been identified as species from the oral cavity. OBJECTIVE To examine the association between the use of acid-suppressive drugs and occurrence of community-acquired pneumonia. DESIGN, SETTING, AN...
Sir, Gaudreau et al. reported a case of group B Streptococcus (GBS) periprosthetic joint infection (PJI) that was treated with oral penicillin (300 mg once daily), but without surgical intervention. After 3 years of suppressive therapy, GBS infection relapsed, and the isolate revealed reduced penicillin susceptibility. A similar case was recently reported by Longtin et al. After 5 years of supp...
Abstract The complexity of the tumor microenvironment (TME) severely hinders therapeutic effects various cancer treatment modalities. TME differs from normal tissues owing to presence hypoxia, low pH, and immune-suppressive characteristics. Modulation reverse growth equilibrium is considered an effective way treat tumors. Recently, polymeric nanomedicines have been widely used in therapy, becau...
OBJECTIVE To evaluate the efficacy of enhanced, intensive, immuno-suppressive therapy with umbilical cord blood support for severe aplastic anemia (SAA). METHODS A total of 25 patients with SAA received enhanced, intensive, immuno-suppressive therapy and a cord blood transfusion. Therapy protocol: Anti-thymocyte globulin (ATG) 2.5 mg/(kg•d) × 5d; Cyclophosphamide 50 mg/(kg•d) × 2d; cyclospori...
A cure of HIV-1 has been achieved in one individual through allogeneic stem cell transplantation with a CCR5[INCREMENT]32 homozygous donor. Whether myeloablation and autologous stem cell transplantation for lymphoma in patients on suppressive antiretroviral therapy can eliminate HIV-1 reservoirs is unknown. Low-level plasma viremia and total HIV-1 DNA and 2-LTR circles in blood mononuclear cell...
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