The synthesis and reactivity of coordinatively unsaturated Rh and Ir complexes supported by the new bis(phosphino)silyl pincer ligand [kappa(3)-(2-Cy(2)PC(6)H(4))(2)SiMe](-) ([Cy-PSiP](-)) are reported, including the first example of facile, room temperature intermolecular arene C-H bond activation mediated by a silyl pincer complex.

We have developed a novel organometallic catalysis and applied it to drug discovery. Two new catalysts were found, ruthenium hydride with a nitrogen-containing heterocyclic carbene (A) and an organopalladium catalyst supported on a sulfur-terminated semiconductor, gallium arsenide (001) (B). Both catalysts are environmentally benign, because A can yield indole derivatives with good atom economy...

Using o-pthaldialdehyde (OPT) fluorescence, the amino acids associated with DNA were studied following exposure of intact Chinese hamster ovary cells to chromate. Rigorous extraction with EDTA, acid, or base was required to release the amino acids cross-linked to the DNA isolated from control or chromate-treated cells by standard procedures (i.e., proteinase K, phenol, etc.). Amino acids resist...

The first highly efficient ligand-controlled regio- and stereodivergent intermolecular hydrosilylations of internal alkynes have been disclosed. Cationic ruthenium complexes [Cp*Ru(MeCN)3](+) and [CpRu(MeCN)3](+) have been demonstrated to catalyze intermolecular hydrosilylations of silyl alkynes to form a range of vinyldisilanes with excellent but opposite regio- and stereoselectivity, with the...

photodegradation of dicamba, an ionizable herbicide, using tio2 supported on hzsm-11 zeolite was investigated. four photocatalysts with different weight percentages (wt%) of tio2 were evaluated: 3%, 10%, 30% and 50%. the effects of the catalyst concentration, the initial ph value and the repeatability of the photocatalytic activity after multiple cycles of reuse were also evaluated. results sho...

In the present research, the selective oxidation of lauryl alcohol to lauraldehyde was studied under liquid-liquid phase transfer conditions using potassium chromate (K2CrO4) as an oxidizing agent and tetrabutyl ammonium bromide (TBAB) as the phase transfer catalyst. Chromium (VI) reagents are used in these oxidations since the alcohols are selectively oxidized <e...

An effective synthesis of nucleosides using glycosyl chlorides as glycosyl donors in the absence of Lewis acid has been developed. Glycosyl chlorides have been shown to be pivotal intermediates in the classical silyl-Hilbert-Johnson reaction. A possible mechanism that differs from the currently accepted mechanism advanced by Vorbrueggen has been proposed and verified by experiments. In practice...

We describe here a Tf₂NH-catalyzed formal (3+3) cycloaddition of silyl enol ethers with acrylates as a new domino reaction. In the domino sequence, the catalyst activates Michael addition, deprotonation of the resulting silyloxonium cation and intramolecular Claisen condensation. It was found that reaction modes significantly depend on the reaction temperature. We also examined the mechanistic ...

S INCE THE INITIAL work of Gray and Sterling,”2 the determination of red cell mass with radioactive sodium chromate has undergone several modifications. Read’ developed the technic of adding ascorbic acid in vitro to the blood-sodium chromate mixture to reduce chromate to trivalent chromium and prevent further uptake by red cells. The inhibition of chromium uptake by ascorbic acid supported the...

Addition of lithium aryl(tetraisopropoxy)titanates [ArTi(OPri)4 Li ] to , -unsaturated ketones proceeded with high enantioselectivity (up to 99% ee) in the presence of an excess amount of chlorotrimethylsilane and a rhodium catalyst (3 mol % Rh), generated from [RhCl(C2H4)2]2 and (S)-binap, in tetrahydrofuran at 20°C to give high yields of the corresponding silyl enolates as 1,4-addition produc...