The major superoxide dismutase ("slow" electromorph) of the fruit fly, Drosophila melanogaster, has been purified to homogeneity. This enzyme contains 2 Cu2+ and 2 Zn2+/molecule. The ultraviolet absorption spectrum indicates a lack of tryptophan. This enzyme has a molecular weight of 32,000 and is composed of two subunits of equal size, which are joined by noncovalent interactions. Cyanide at 1...

Previous studies demonstrated a significant reduction of ultimate infarct size in the canine heart by the combined administration of superoxide dismutase plus catalase. This study was performed to assess the independent effects of each enzyme on ultimate infarct size due to ischemia/reperfusion. Dogs received 2-hour infusions of superoxide dismutase, catalase, or albumin (controls) via the left...

OBJECTIVE This study assessed the relationship between the parameters of glycemic control, and zinc concentrations in blood and superoxide dismutase enzyme activity in type 2 diabetes patients. SUBJECTS AND METHODS Seventy-three individuals, aged between 25 and 59 years, were divided into the experimental group (type 2 diabetes patients, n = 36) and control group (n = 37). Plasma and erythroc...

background: the aim of this study was to compare superoxide dismutase (sod) activity in fasciola hepatica and fasciola gigantica parasites. materials: f. gigantica and f. hepatica helminths were collected from abattoir and cultured in buffer media for 4 h at 37 °c. excretory-secretory (es) products were collected, centrifuged and stored at - 20 ◦ c. e-s protein concentration was measured by bra...

conclusions consumption of ole after tumor transplantation reduced the tumor growth. on the other hand, owing to its highly-packed polyphenols, catalase and superoxide dismutase activities in tumor tissue were increased. results treatment with 150 and 225 mg/kg/day of ole reduced the tumor volume and weight (p < 0.05) compared to the first group significantly. it also increased the cat activity...

patients and methods manganese superoxide dismutase polymorphism was genotyped using polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) in 103 patients with mlds and 103 healthy control subjects. conclusions according to the fact that mn-sod gene polymorphisms have been considered as a major risk factor in some malignancies, this single center study did not find any a...

the aims of this study were to assess the effects of drought stress on peroxidase (pod), superoxide dismutase (sod) and catalase (cat) activities as well as free proline content and growth parameters of pistacia khinjuk seedlings under drought stress. therefore, the one-year seedlings of pistacia khinjuk subjected to water stress (25%, 50%, 75%, and 100% field capacity) for 8 months in greenhou...

cadmium is considered as a common residue in water and sediments which could readily enter aquatic organisms. the aim of this study was to evaluate the time- and concentration-dependent changes in antioxidant enzymes (sod and cat) activities as well as concentration of mda as a bi- product of lipid peroxidation in the liver of persian sturgeon, acipenser persicus , following cdcl 2 exposure at ...

introduction: considering the prevalence of epilepsy and the failure of available treatments for many epileptic patients, finding more effective drugs in the treatment of epilepsy seems necessary. oxidative stress has a special role in the pathogenesis of epileptic syndrome. therefore, in the present study, we have examined the anti-epileptic and anti-oxidant properties of the ferula assa foeti...