The purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (SS) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. The influence of various permeation enhancers, such as dimethyl sul...

Abstract Industrial wastes such as granite waste powder (GWP), GGBS, and Metakaoline (MK) are widely available in numerous Indian states. Due to their pozzolanic abilities, GGBS were used a partial alternative cement the manufacture of concrete, with constant levels 40% 10% Metakaoline. In addition, minimize use natural resources, was fine aggregate substitute various percentages (0, 10%, 20%, ...

OBJECTIVES A Box-Behnken design was used for evaluation of Eudragit coated diclofenac pellets. The purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. MATERIALS AND METHODS Diclofenac was loaded onto the non-pareil beads using conventional coating pan. Film coating of pellets was done at the same pan. The effect of plast...

Earlier work with pure cultures had shown that the interaction of microbes with plasticizers leads to the formation of metabolites including 2-ethylhexanoic acid and 2-ethylhexanol that resist further degradation. The presence of these metabolites is now reported in a variety of environmental samples. Thus, even in a complex ecosystem, when plasticizers are degraded, the breakdown is not comple...

Liquid -caprolactone (CL) oligomers were synthesized by a ring-opening reaction of CL using a propylene glycol (PPG) as the initiator for use as new plasticizers of poly (L-lactide) (PLA) films. PPG-CL oligomers containing two (PPG-2CL) and four (PPG-4CL) units of CL at both PPG end-chains were prepared. The PLA/oligomer blend films were prepared by solution blending before film casting. The t...

Hydroxypropyl methylcellulose (HPMC)–coated papers without plasticizer and plasticized with polyols were prepared, and the effects of coating weight, different plasticizers (glycerol (GLY), sorbitol (SOR), and polyethylene glycol (PEG)), and plasticizer contents (20% to 50%) on the physical and mechanical properties of the resulting biopolymer-coated papers were studied. Coating weight was the ...

Plasticizers are commonly added to poly(vinyl chloride) (PVC) and other brittle polymers to improve their flexibility and processing properties. Phthalate plasticizers such as di(2-ethylhexyl phthalate) (DEHP) are the most common PVC plasticizers and have recently been linked to a wide range of developmental and reproductive toxicities in mammals. Our group has developed several replacement com...

New solid polymer electrolytes (SPE) based on poly(ethylene oxide) (PEO) doped with lithium trifluoromethanesulfonate (LiCF3SO3), dibutyl phthalate (DBP) plasticizer, and zirconium oxide (ZrO2) nanoparticles were prepared by solution-casting technique. The conductivity was enhanced by addition of dibutyl phthalate (DBP) plasticizer and ZrO2 nanofiller with maximum conductivity (1.38 × 10(-4) Sc...