The title compound, C(19)H(17)ClN(4)O(3)S, is a Schiff base compound of 5-chloro-salicylaldehyde and sulfamethazine [4-amino-N-(4,6-dimethyl-2-pyrimidin-yl)benzene-sulfonamide]. The geometry around the S atom is distorted tetra-hedral, comprising two O atoms of the sulfonyl group, a C atom of a benzene ring and the amino N atom. The title compound has an intra-molecular O-H⋯N hydrogen bond and ...

Sulfamethazine (SMT) is a sulfonamide antibacterial drug used to treat or prevent infections in both humans and animals. However, SMT exhibits unfavorable taste poor compaction behavior. To ove...

The photoelectrocatalytic degradation and mineralization of sulfamethazine (SMT), a sulfonamide drug, were explored in aqueous solution. Working electrodes with TiO2 coatings on Ti substrates (TiO2/Ti) used, which produced by the dip coating method. film analyzed scanning electron microscopy (SEM) X-ray diffraction (XRD) following annealing at 500 °C for 1.5 h. To photoelectrochemically charact...

The metabolism of sulfamethazine (SMZ), which is acetylated by a binodally distributed enzyme, and procainamide (PA) was compared in 21 normal volunteers, each given a single oral dosted metabolites, N-acetyl-procainamide (NAPA) and Ac-SMZ, were measured. Subjects with less than 64% Ac-SMZ in the 0-8 hour collection were termed "slow" and those with more than 64% were termed "fast" SMZ acetylat...

We report the draft genome sequence of Microbacterium sp. strain C448, isolated from agricultural soil with a decade of exposure to veterinary antibiotics on the basis of using sulfamethazine and other antibiotics as the sole sources of carbon. The genome sequence revealed that strain C448 harbors several antibiotic resistance genes, including sulI.

The method for sulfamethazine using post column derivatization (Associate Referee Robert Smallidge) was adopted First Action in 1999. There are a number of methods which could be readied for collaborative study with relatively little work, i.e., carbadox, ethopabate, lasalocid, or morantel tartrate. In addition to the remarks made for the following Associate Referee topics, readers can refer to...