نتایج جستجو برای: sublingual misoprostol
تعداد نتایج: 5828 فیلتر نتایج به سال:
BACKGROUND To identify an effective misoprostol-only regimen for the termination of second trimester pregnancy, we compared sublingual and vaginal administration of multiple doses of misoprostol in a randomized, placebo-controlled equivalence trial. METHODS Six hundred and eighty-one healthy pregnant women requesting medical abortion at 13-20 weeks' gestation were randomly assigned within 11 ...
Objective: To compare the efficacy of misoprostol 50 μg vaginally and 50 μg sublingually for labor induction at term. Materials and Methods: One hundred and twenty women were randomized to receive misoprostol 50 μg vaginally (n = 60) or 50 μg sublingually misoprostol (n = 60). The doses were g iven every 5 h (maximum 5 doses). Primary outcome measure was vaginal delivery rate. Induction to deli...
OBJECTIVE To identify an effective misoprostol-only regimen for termination of pregnancy between 12 and 20 weeks of gestation, a prospective randomized study comparing sublingual, vaginal, and oral routes of administration of misoprostol was done. METHODS One hundred and fifty women (12-20 weeks gestation) were randomly divided into three groups and given 400 mcg misoprostol sublingually, vag...
BACKGROUND AND OBJECTIVES Misoprostol would reduce the uterine bleeding after cesarean delivery without harmful effects on either mother or baby. We aimed to evaluate the effects of preoperative misoprostol on maternal blood loss, uterine tone, and the need for additional oxytocin after cesarean delivery under isoflurane anesthesia. METHODS After ethical approval, 366 patients scheduled for e...
The current gold standard for treating postpartum hemorrhage (PPH) due to atony is intravenous (IV) oxytocin1. However, access to this specific drug and the capacity for its timely intravenous administration are lacking in settings with limited resources, especially at lower levels of the health care system. Misoprostol, a tablet that requires no additional supplies and/or specialized skills to...
OBJECTIVE To evaluate whether routine administration of sublingual misoprostol 600 microg after delivery reduces postpartum haemorrhage. DESIGN Randomised double blind placebo controlled trial. SETTING Primary health centre in Bissau, Guinea-Bissau, West Africa. PARTICIPANTS 661 women undergoing vaginal delivery. INTERVENTION Misoprostol 600 mug or placebo administered sublingually imme...
Background: Labor induction is one of the most public ways carried out global for delivering mothers. The aim of labor induction is to encourage uterine contractions before the spontaneous onset of labor, resultant in vaginal delivery misoprostol is used off-label for a variety of indications in the practice of obstetrics and gynecology, including medication abortion, medical management of misc...
OBJECTIVES To compare the efficacy of labour induction using sublingual misoprostol versus combined artificial rupture of membranes and oxytocin infusion for nulliparous women with a favourable cervix at term. DESIGN Open randomised controlled trial. SETTING Regional hospital, Hong Kong. PATIENTS Fifty nulliparous women with a favourable cervix (Bishop score 6 or more) at term and indicat...
Misoprostol is an effective and safe uterotonic for the prevention and treatment of postpartum hemorrhage (PPH). A 600-μg oral dose of misoprostol has been shown to prevent PPH in community-based randomized controlled trials. An 800-μg sublingual dose of misoprostol appears to be a good first-line treatment for controlling PPH. Adverse effects after use of misoprostol for PPH prevention or trea...
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