نتایج جستجو برای: subinhibitory concentrations

تعداد نتایج: 306940  

Journal: :Journal of bacteriology 2015
Matthew J Powers Edgardo Sanabria-Valentín Albert A Bowers Elizabeth A Shank

UNLABELLED Interspecies interactions have been described for numerous bacterial systems, leading to the identification of chemical compounds that impact bacterial physiology and differentiation for processes such as biofilm formation. Here, we identified soil microbes that inhibit biofilm formation and sporulation in the common soil bacterium Bacillus subtilis. We did so by creating a reporter ...

Journal: :Antimicrobial agents and chemotherapy 2000
S Rachid K Ohlsen W Witte J Hacker W Ziebuhr

Biofilm production is an important step in the pathogenesis of Staphylococcus epidermidis polymer-associated infections and depends on the expression of the icaADBC operon leading to the synthesis of a polysaccharide intercellular adhesin. A chromosomally encoded reporter gene fusion between the ica promoter and the beta-galactosidase gene lacZ from Escherichia coli was constructed and used to ...

Journal: :Antimicrobial agents and chemotherapy 2007
Oana Dumitrescu Sandrine Boisset Cedric Badiou Michele Bes Yvonne Benito Marie-Elisabeth Reverdy François Vandenesch Jerome Etienne Gerard Lina

We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.

Journal: :Antimicrobial agents and chemotherapy 2011
Kristen N Kindrachuk Lucía Fernández Manjeet Bains Robert E W Hancock

The adaptive resistance of Pseudomonas aeruginosa to aminoglycosides is known to occur during chronic lung infections in cystic fibrosis patients in response to nonlethal concentrations of aminoglycosides. Not only is it difficult to achieve high levels of drug throughout the dehydrated mucus in the lung, but also steep oxygen gradients exist across the mucus layer, further reducing the bacteri...

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