while a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (sah), the most consistent is endothelial damage. since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following sah. this experimental study investigates the correlation between endothel...

Spontaneous anterior cerebral artery (ACA) dissection, although extremely rare, is often associated with severe morbidity and mortality. It could lead to cerebral hemorrhage, ischemic stroke, or, rarely, combination of hemorrhage and ischemia due to hemodynamic changes. Prompt and accurate diagnosis is essential for determining the appropriate management. However, the optimal treatment for ACA ...

BACKGROUND AND PURPOSE We examined the therapeutic effect of human extracellular superoxide dismutase (ECSOD) gene transfer in the prevention of delayed cerebral vasospasm after experimental subarachnoid hemorrhage (SAH) because it was reported ECSOD relieved early-stage vasospasm. METHODS Twenty mongrel dogs were divided randomly into 4 groups to serve as control, SAH, SAH+adenovirus ECSOD (...

OBJECTIVE To investigate the difference between myocardial injuries caused by nonaneurysmal subarachnoid hemorrhage (SAH) or aneurysmal SAH. PATIENTS AND METHODS A total of 92 inpatients with SAH at early stage (within 48h), who were treated in our hospital from 2008 to 2014 were enrolled in this study. Differences in cerebral-cardiac syndrome seen in perimesencephalic subarachnoid hemorrhage...

 Background and Aim: Secondary complications management of Subarachnoid Hemorrhage (SAH) is one of the therapeutic challenging issues during ICU[A1]  admission. The complications of patients with SAH admitted to the ICU of Imam Khomeini Hospital of Urumia were investigated in this study. Methods and Materials/Patients: In this descriptive study, the clinical complications of the patients with ...

Aneurysmal subarachnoid hemorrhage (SAH) carries high early patient mortality. More women than men suffer from SAH and the average age of female SAH survivors is greater than that of male survivors; however, the overall mortality and neurological outcomes are not better in males despite their younger age. This pattern suggests the possibility of gender differences in the severity of initial imp...

Early brain injury (EBI) after subarachnoid hemorrhage (SAH) is characterized by a severe, cerebral perfusion pressure (CPP)-independent reduction in cerebral blood flow suggesting alterations on the level of cerebral microvessels. Therefore, we aimed to use in-vivo imaging to investigate the cerebral microcirculation after experimental SAH. Subarachnoid hemorrhage was induced in C57/BL6 mice b...

Headache is a common chief complaint in primary and ambulatory care settings. The etiology of headache is usually benign, its workup is often minimal and straightforward, and the clinical approach focuses primarily on symptom control. A small proportion of headaches is caused by subarachnoid hemorrhage (SAH), most of which are due to ruptured cerebral aneurysms. Such hemorrhage carries a high m...

Aneurysmal subarachnoid hemorrhage (A-SAH) has potentially devastating consequences acutely, sub-acutely and long term. The incidence of A-SAH varies widely among populations with up to a tenfold difference. Incidence ranges from 2.0 per 100,000 per year in China to 22.5 per 100,000 per year in Finland.1 One of the most feared complications in patients who survive the acute A-SAH is cerebral va...

Introduction: The occurrence of subarachnoid hemorrhage (SAH) in traumatic brain injury (TBI) is 12% ~ 53% and related to poor outcome (1, 2). Early diagnosis of SAH and active intervention in removing hemorrhage from subarachnoid space is of great significance in the management of acuteTBI. Susceptibility weighted imaging (SWI) has been successfully applied in TBI and proved to be 6 times more...