We have generated a mouse model for hepatocellular carcinoma using somatic delivery of oncogene-bearing avian retroviral vectors to the liver cells of mice expressing the viral receptor TVA under the control of the albumin gene promoter (Alb-TVA mice). Viruses encoding mouse polyoma virus middle T antigen (PyMT) induced tumors, which can be visualized with magnetic resonance imaging, in 65% of ...

In combination with whole report and partial report tasks, the theory of visual attention (TVA) can be used to estimate individual differences in five basic attentional parameters: the visual processing speed, the storage capacity of visual short-term memory, the perceptual threshold, the efficiency of top-down selectivity, and the spatial bias of attentional weighting. TVA-based assessment has...

We have previously described an approach that employs retroviral receptor-ligand bridge proteins to target retroviral vectors to specific cell types. To determine whether targeted retroviral entry can also be achieved using a retroviral receptor-single-chain antibody bridge protein, the TVA-MR1 fusion protein was generated. TVA-MR1 is comprised of the extracellular domain of the TVA receptor fo...

BACKGROUND Development of tricuspid regurgitation after orthotopic heart transplantation can cause heart failure along with renal and hepatic impairment and portends a poor prognosis. If tricuspid regurgitation causes significant symptoms, tricuspid valve repair or replacement is often required. This study was designed to study the effects of prophylactic tricuspid valve annuloplasty (TVA) duri...

with the prolonged use of domestic centrifugal pump, due to erosion, corrosion and an unbalance the sever vibration of the pump are resulted. an erratic sound coming out of pump makes the user uncomfortable. here, tuned vibration absorber (tva) is used as a vibration controlling device. it is designed to reduce the rms velocity below 20% of the circumferential speed, at which the impeller is ba...

Background: Adenomas are assumed to be the precursors of colorectal cancer. Aim was to study the epithelial and stromal components of various histological types of rectal adenomas. For evaluation of condition of all the components of neoplasia we have introduced a term “communicative systems” which consists of microcirculatory vessels and vegetative nerve terminals and the cell populations surr...

We examined the relationship between commonly measured features of cranial muscle activity and the magnitude of sub- and superambient pressure measured inside the buccal cavity of the striped burrfish Chilomycterus schoepfi during inflation behavior. Buccal pressure was recorded simultaneously with electromyographic (EMG) records of activity from three expansive-phase muscles (levator operculi,...

We are using avian leukosis-sarcoma virus (ALSV) vectors to generate mouse tumor models in transgenic mice expressing TVA, the receptor for subgroup A ALSV. Like other classical retroviruses, ALSV requires cell division to establish a provirus after infection of host cells. In contrast, lentiviral vectors are capable of integrating their viral DNA into the genomes of nondividing cells. With the...

This chapter examines issues and methods for survivability of systems under malicious penetrating attacks. To protect from such attacks, it is necessary to take steps to prevent them from succeeding. At the same time, it is important to recognize that not all attacks can be averted at the outset; those that are partially successful may be unavoidable, and comprehensive support is required for i...

The relation between proliferation and apoptosis was studied in colorectal mucosal biopsies (N = 41), tubular adenomas (TA) (N = 104) and tubulovillous adenomas (TVA) (N = 34) from 37 FAP patients. Proliferative activity was determined by cell cycle distribution analysis. In addition, transcriptional capacity was determined by chromatin in situ testing. For both, DNA flow cytometry was used. Cy...