I study the relation between firm debt structure and future financial flexibility. I consider how the total level of debt, maturity, security, and priority may potentially impact a firm’s ability to raise new financing and undertake profitable investments. I find that firms with lower total debt (high debt capacity) are more financially flexible. Lower leverage increases future new debt issues ...

Modeling protein flexibility is a long standing challenge in computational biology with a special impact to protein docking. Relating problems are protein structures alignment and identification of flexible and rigid protein regions, as well as a general definition of a region degree of flexibility. Determination of protein flexibility from a single protein conformation, so called apriori appro...

The multidomain zinc endopeptidase matrix metalloproteinase-9 (MMP-9) is a recognized therapeutic target in autoimmune diseases, vascular pathologies, and cancer. Despite its importance, structural characterization of full-length pro-MMP-9 is incomplete. Here, we report the structural model of full-length pro-MMP-9 and, in particular, the molecular character of its unique proline-rich and heavi...

the objective of this study was to develop a new optimal parallel algorithm for matrix multiplication which could run on a fibonacci hypercube structure. most of the popular algorithms for parallel matrix multiplication can not run on fibonacci hypercube structure, therefore giving a method that can be run on all structures especially fibonacci hypercube structure is necessary for parallel matr...

the purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. matrix system was the earliest oral extended release platform for medicinal use. matrix tablets are most commonly used methods to modulate the release profile of drugs. they are much desirable and preferred for such therapy because they offer be...

This chapter describes marketing strategies in concept for wireless broadband services in the Sri Lankan market. It also emphasizes different technologies offering fixed and mobile broadband services. Wi-Fi services which are mentioned here has been on offer for few years but actual marketing of such services are not actively done in Sri Lanka. Various marketing strategies that could be used to...

The flexibility matrix currently forms the basis for multibody dynamics models of cervical spine motion. While studies have aimed to determine cervical motion segment behavior, their accuracy and utility have been limited by both experimental and analytical assumptions. Flexibility terms have been primarily represented as constants despite the spine's nonlinear stiffening response. Also, nondia...

In recent years the aluminum matrix composites are gaining wide spread applications in automotive, aerospace, defense, sport and other industries. The reason for this is their exciting properties like high specific strength, stiffness, hardness, wear resistance, dimensional stability and designer flexibility. The present work reports on mechanical properties and microstructure analysis of Al-Si...