Results: Serum soluble corin level was significantly higher in ischemic stroke patients than hemorrhagic stroke patients in men (log-corin, mean±SD:7.53±0.34 vs. 7.42±0.28; P =0.013) and women (log-corin, mean±SD:7.22±0.27 vs. 7.12±0.31; P = 0.044). Then we studied serum soluble corin in subtypes of ischemic stroke. Unadjusted analysis failed to show a significant difference in logtransformed s...

BACKGROUND AND PURPOSE Population-based stroke incidence studies are the only accurate way to determine the number of strokes that occur in a given society. Because the major stroke subtypes have different patterns of incidence and outcome, information on the natural history of stroke subtypes is essential. The purpose of the present study was to determine the incidence and case-fatality rate o...

OBJECTIVE To identify the frequency of risk factors in various subtypes of acute ischemic stroke according to TOAST criteria. STUDY DESIGN Cross-sectional, observational study. PLACE AND DURATION OF STUDY Ziauddin Hospital, Karachi, from January to December 2007. METHODOLOGY Patients with acute ischemic stroke were enrolled. Studied variables included demographic profile, history of risk ...

The purpose of this study was to analyze the outcomes and complications between stroke subtypes after intravenous thrombolysis. A total of 471 patients with acute ischemic stroke after intravenous thrombolysis from January 2007 to April 2014 were enrolled and classified according to the Trial of Org 10172 in Acute Stroke Treatment. A multivariate logistic regression model was used to evaluate t...

BACKGROUND AND PURPOSE C-reactive protein (CRP) has evolved as an inflammatory risk marker of cardiovascular disease. Several single-nucleotide polymorphisms at the CRP locus have been found to be associated with CRP levels. The aim of the present study was to investigate CRP levels and genetic variants in etiological subtypes of ischemic stroke. METHODS The Sahlgrenska Academy Study on Ische...

BACKGROUND Cerebral infarction caused by different reasons seems differ in fibrinogen levels, so the current work intends to explore the relationship between the fibrinogen level and subtypes of the TOAST criteria in the acute stage of ischemic stroke. METHODS A total of 577 case research objects were treated acute ischemic stroke patients in our hospital from December 2008 to December 2010, ...

BACKGROUND AND PURPOSE The nature of hematologic disorders in different stroke subtypes remains uncertain. The purpose of this study was to clarify the differences in the coagulation and fibrinolytic activities among ischemic stroke subtypes. METHODS We performed sequential measurements of hematologic parameters in 21 patients with acute cardioembolic stroke, 10 patients with atherothrombotic...

BACKGROUND AND PURPOSE Results from twin and family history studies of ischemic stroke suggest that future molecular genetic studies should focus on strictly defined stroke subtypes and younger cases. Accordingly, we investigated stroke subtypes, vascular risk factors, and family history in a large study of patients with ischemic stroke onset before age 70 years. METHODS Six hundred consecuti...

BACKGROUND The purpose of this study was to analyze the epidemiological trend and distribution of stroke mortality in the city of Tianjin, China, in order to provide evidence for the prevention and control of stroke. METHODS The study was based on 102 718 cases of stroke mortality in Tianjin between 1999 and 2006. The cause of death was coded according to the International Classification of D...