insulin dependent diabetes mellitus (iddm) results from irreversible loss of beta cells (β-cells) of the pancreas. a streptozotocin (stz)-induced diabetes in animal model mimics, in some aspects, recent onset iddm. this study was conducted to investigate the effect of nicotinamide on experimentally-induced iddm. thirty spraque dawley rats were divided into 3 groups; a control group, a diabetic ...

background: the cardiac effects simultaneously occurring during experimental hypertension and diabetes have rarely been investigated. this study aimed at examining the effects of short-term renovascular hypertension and type 2 diabetes on cardiac functions. methods: five groups (7 each) of male sprague-dawley rats, including a control group, a diabetes (induced by streptozocin and nicotinamide)...

diabetes is characterized by a nitric oxide deficiency at the wound site. diabetes is a factor that influences all stages of wound healing. in animals with acute experimental diabetes induced by streptozotocin (stz), the early inflammatory responses after wounding is impaired, fibroblast and endothelial cell proliferation is reduced as well as accumulation of reparative collagen and gain in wou...

Herbal medicine development against the non-communicable disease like diabetes is one of the thrust area of research in the field of global medicine. Here we have studied the separate and composite methanolic extract of seed of Eugenia jambolana and root of Musa paradisiaca for the management of streptozotocin-induced diabetes mellitus. We have measured the fasting blood glucose level and glyco...

Objective(s): Reproductive dysfunction is a consequence of diabetes. Diabetes is associated with changes in testicular tissue. Sesame oil contains large amounts of polyunsaturated fatty acids and lignin with antioxidant activity, vitamin E, and monounsaturated fatty acid (MUFA). The present study investigated the effects of sesame on testis histology and male reproductive parameters in streptoz...