نتایج جستجو برای: streptozocin

تعداد نتایج: 7580  

B. P. Nagori, G. K. Singh, M. Pharm, Nilesh Jain, Pradeep Goyal,

Evaluation of hypoglycemic activity of inflorescence of Borassus flabellifer extract in male wistar rats has been investigated. Antidiabetic potentials were studies by the orally administration of plant extract at the doses of 150, 300 and 600 mg/kg in streptozocin-induced diabetic male wistar rats. Treatment of streptozocin-induced diabetic male wistar rats with the extracts caused a signifi...

Journal: :iranian journal of diabetes and obesity 0
hamid reza jamshidi department of toxicology-pharmacology, faculty of pharmacy, yazd shahid sadoughi university of medical sciences, yazd iran. mohammad hossein mosaddegh department of toxicology-pharmacology, faculty of pharmacy, yazd shahid sadoughi university of medical sciences, yazd iran. ali reza vahidi herbal medicine center, shahid sadoughi university of medical sciences, yazd, iran. mona ghasemian student in pharmacy, shahid sadoughi university of medical sciences, yazd, iran. nahid haj mohammadi student in pharmacy, shahid sadoughi university of medical sciences, yazd, iran.

objective: herbal medicine and medical plants such as ziziphus jujuba are widely used in the treatment of diseases such as diabetes mellitus. we investigated the effects of ethanol extracts of ziziphus jujuba fruit on serum glucose, triglycerides, ldl-cholesterol, hdl-cholesterol, cholesterol and activities of aminotransferase enzymes in streptozocin-induced diabetic adult male rats. materials ...

Journal: :iranian journal of toxicology 0
الهام قنبری elham ghanbari msc. of histology and embryology, department of biology, urmia university, urmia, iran. وحید نجاتی vahid nejati department of biology, urmia university, urmia, iran. مهری آزادبخت mehri azadbakht department of biology, razi university, kermanshah, iran.

background: royal jelly has been shown to have antioxidant and antidiabetic effects. the objective of this study was to evaluate the protective effect of rj against kidney damage in streptozotocin induced diabetic rats. methods: thirty two male wistar rats were divided randomly into four groups (n=8 per group). normal control and diabetic control groups received 1cc/day distilled water, normal ...

2012
Uğur Fırat Savaş Kaya Abdullah Çim Hüseyin Büyükbayram Osman Gökalp Mehmet Sinan Dal Mehmet Numan Tamer

Eryptosis is a term to define apoptosis of erythrocytes. Oxidative stress and hyperglycemia, both of which exist in the diabetic intravascular environment, can trigger eryptosis of erythrocytes. In this experimental study, it is presented that the majority of erythrocytes shows caspase-3 immunoreactivity in streptozocin- (STZ)-induced diabetic rats. Besides that, caspase-3 positive erythrocytes...

Journal: :Investigative Opthalmology & Visual Science 2011

Journal: :Diabetes 1990
O Pedersen J F Bak P H Andersen S Lund D E Moller J S Flier B B Kahn

Studies of experimental diabetes in rodents induced by the beta-cell toxin streptozocin have shown that the insulin-resistant glucose transport of peripheral tissues (muscle and adipose) in these animals can be ascribed in part to a pretranslational reduction of the major insulin-sensitive glucose transporter (GLUT4) in these tissues. Because a central feature of non-insulin-dependent diabetes ...

Journal: :International journal of clinical and experimental medicine 2014
Chun Yang Bin Zhu Fei Hua

Several lines of evidence have demonstrated that leptin is probably involved in the cognitive impairment which induced by a single injection of streptozocin (STZ). However, there is little literature reporting the relationship between cognitive impairment and cardiopulmonary bypass (CPB). This study aimed to investigate the role of leptin in the cognitive impairment of STZ-induced diabetic rats...

2013
Richard N. Fedorak

To examine the pattern and mechanism of enhanced intestinal nutrient absorption in diabetes, we measured intestinal transport of 3-0-methylglucose (30MG), I-alanine (ALA), and SO4 in male Lewis rats made diabetic with streptozocin. Diabetes enhanced 30MG absorption fivefold in ileum and threefold in jejunum; ALA absorption increased twofold in ileum but not at all in jejunum; ileal S04 transpor...

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