CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well patient clinician perspectives, a drug or class.
 The inform non-binding recommendations that help guide decisions Canada's federal, provincial, territorial governments, with exception Quebec.
 This review assesses Dalbavancin (Xydalba) for injection, 500 mg (...

Institute of Dental Research Westmead Millennium Institutes Westmead Centre for Oral Health PO Box 533 Wentworthville NSW 2145 Tel (02) 98458772 Fax (02) 98457599 E-mail: [email protected] Infective endocarditis (IE) is a life threatening, endovascular infection occurring when bacteria enter the blood stream and adhere to heart valves. Mortality rates remain in the range of 1127% ....

INTRODUCTION Organisms of the Streptococcus milleri group consists of Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus. Though they are commonly associated with abscesses, bacteremia with subsequent septic shock and mortality is infrequent. CASE PRESENTATION We report a case of a 27-year-old Chinese man who presented with Streptococcus constellatus bacteremia...

"Streptococcus milleri" is an unofficial name that has been applied to a group of streptococci which, although basically similar, show various hemolytic, serological, and physiological characteristics. The species name Streptococcus anginosus has recently been recognized as the approved name for these organisms. Streptococci known as "S. milleri" have been implicated as etiologic agents in a va...

In the August issue of the Journal of Clinical Microbiology, Hadid and colleagues reported an interesting case of Streptococcus anginosus endocarditis complicated with endophthalmitis (3). The case illustrated the old concept of Sutton’s law with another perspective. The case reported had a fundal picture suspicious of a fungal infection. Together with the presence of fever and the constellatio...

A collection of dead white blood cells within the liver is called a liver abscess, and pyogenic liver abscess (PLA) is the most common type. PLA is commonly associated with biliary tract infections. However, in this case report, we present a rare cause of Streptococcus anginosus bacteremia and PLA which is associated with a carcinoma of the colon at the splenic flexure. The presentation mimicke...

INTRODUCTION Streptococcus intermedius - a member of the Streptococcus anginosus group - is part of the normal microbial flora of the oral cavity. Despite being regarded as a harmless apathogenic commensal, Streptococcus intermedius has been described to cause abscesses in various locations of the body. CASE PRESENTATION We report the clinical case and course of treatment of a 18-year-old mal...

The production of mannosidase activity by all currently recognized species of human viridans group streptococci was determined using an assay in which bacterial growth was dependent on the degradation of the high-mannose-type glycans of RNase B and subsequent utilization of released mannose. RNase B is an excellent substrate for the demonstration of mannosidase activity since it is a glycoprote...