One of the major challenges in developing a highly effective experimental plan to optimize the design space of a manufacturing process is the highly complex nature of the pharmaceutical manufacturing processes. Response surface methodology (RSM) techniques are widely used in pharmaceutical research and are the method of choice for demonstrating robust process which is as per regulatory requirem...

Present work was aimed for the design of phosphated cross-linkedmicrospheres ofmongo gum (MG) by emulsification method using sodium-tri-meta phosphate (STMP) as a crosslinking agent for treatment of colon cancer using Methotrexate (MTX) as model drug.At a stirring speed of 1000rpm and about 5h of stirring time was found to be optimal to obtain reproducible microspheres.The particle size was inc...

Department of Metallurgy and Materials Engineering, Mehran University of Engineering & Technology (MUET) Jamshoro 76080, Pakistan. Dept of Mining Engineering, MUET Jamshoro 76080, Pakistan, Departmen of Mineral Processing and Petroleum Engineering, Montan University Leoben, Austria. -----------------------------------------------------------------------------------------------------------------...

nisin has numerous applications as a natural preservative in foods, including dairy product, canned food, processed cheese and milk. several studies demonstrated that proteolytic degradation and the interaction of nisin with food components might result in decreased its antimicrobial activity. encapsulation of antimicrobial peptides into nanoliposomes may offer a potential alternative to protec...

The effects of mechanical stress during emulsification on the oxidation of methyl linoleate were investigated by four methods (high-pressure homogenization, high-speed stirring, ultrasonic homogenization, and membrane emulsification). The oxidation rates and induction periods were almost constant, regardless of the emulsification method, except for membrane emulsification, by which the inductio...

The filter cake, generated from the cold-purification stage in a zinc electrowinning plant and considered as a hazardous waste containing heavy metals, was characterized for its chemical and mineralogical compositions by inductively couple plasma-optical emission spectroscopy (ICP-OES), X-rays diffractometry (XRD) and scanning electron microscopyenergy dispersive X-rays spectrometry (SEM-EDS). ...

The ion exchange resin Amberlite 958 was used to investigate its behaviour on the removal of hazardous vanadium(V) from aqueous media. This investigation carried out under various hydrodynamic conditions and chemical conditions, such as variation stirring speed, pH solution, dosage, initial in temperature. Vanadium(V) uptake onto highly dependent thus, speciation this phase; process had an endo...