SUMMARY Gastaut noted that there are as many forms of status epilepticus (SE) as there are seizure types. The pleomorphic EEG patterns reflect this wide variety of clinical types. The different electroclinical types of status epilepticus share EEG characteristics including rhythmic activity, epileptiform discharges, and often a waxing and waning evolution. Gray zones of interpretation exist in ...

*Authors contributed equally 8 Running title: Status epilepticus alters dentate basket cell tonic inhibition 9 Abstract 37 Temporal lobe epilepsy is associated with loss of interneurons and inhibitory dysfunction in the 38 dentate gyrus. While status epilepticus (SE) leads to changes in granule cell inhibition, whether 39 dentate basket cells critical for regulating granule cell feed-forward an...

objecive prolonged and uncontrolled refractory status epilepticus (se) is a life-threatening medical emergency in children (1,2,3). there is no consensus on the optimal therapy for refractory status epilepticus (1). the aim of this study was to develop a new method for treating patients with refractory status epilepticus. materials & methods ten children with refractory status epilepticus in mo...

MicroRNA (miRNA) are an important class of non-coding RNA which function as post-transcriptional regulators of gene expression in cells, repressing and fine-tuning protein output. Prolonged seizures (status epilepticus, SE) can cause damage to brain regions such as the hippocampus and result in cognitive deficits and the pathogenesis of epilepsy. Emerging work in animal models has found that SE...

Seizures are a common and potentially devastating clinical problem in small animal practice. Epidemiologic studies indicate that epilepsy affects approximately 5% of the canine population, and 60% of canine epileptics will experience status epilepticus (SE) or other emergent seizure semiology in their lifetime. Seizures disorders, including status epilepticus, are among the most common presenti...

Received: 06/25/2007 Approved: 12/18/2007 Portugu se / English: www.scielo.br/reeusp RESUMO Este é um estudo exploratório de natureza quantitativa e qualitativa, que avalia o desempenho dos serviços de saúde na execução do DOT no domicílio em um município de grande porte. Para a análise quantitativa foram construídos indicadores que avaliaram a otimização dos recursos materiais/ humanos e a efe...

PURPOSE Status epilepticus (SE) is an important neurological emergency. Early diagnosis could improve outcomes. Traditionally, SE is defined as seizures lasting at least 30 min or repeated seizures over 30 min without recovery of consciousness. Some specialists argued that the duration of seizures qualifying as SE should be shorter and the operational definition of SE was suggested. It is uncle...

The most common thresholds for considering prolonged seizures as status epilepticus (SE) are 5 and 30 min. It is unknown whether these different thresholds (5 or 30 min) identify patient populations with different electroclinical characteristics. We compared the characteristics of patients with SE lasting 5-29 min (SE5-29) with those with SE lasting ≥30 min (SE≥30). Inclusion criteria were the ...

Background and Objective: Status epilepticus (SE) is the most severe and feared form of epilepsy. The overall incidence of SE varies from 10 to 60 per 100,000 person-years, and the mortality is approximately 20% with 15 to 20% for adults and 3 to 15% for children. Chronic epilepsy often MTLE (20-40%), permanent neurologic defi cits (9 to 11%) and encephalopathy (6 to 15%) are probably caused by...