background: tumor response after multimodality treatment using combination of radiation, chemotherapeutic drugs and hyperthermia usually assessed by parameters such as tumor growth delay, volume doubling time and regression response. the study herein was conducted to investigate the usefulness of micronucleus assay for assessing the multimodality treatment. materials and methods: the induction ...

The methanolic leaf extract of Artemisia parviflora (APLE) tested against Anopheles stephensi larvae and pupae and recorded the mortality rate, LC 50 and LC 90 values. This investigation revealed that this leaf extract possess higher toxicity against Anopheles stephensi. The biological activity of the plant extract might be due to the presence of active compounds âCaryophyllene, germacrene D, C...

Background Cardiac involvement of sarcoidosis (CIS) in progressed and advanced stage increases cardiac events and mortality of systemic sarcoidosis, so early diagnosis and determination of disease activity are needed for treating in CIS. However, evaluating disease activity of CIS remains a major challenge because no single diagnostic test has yet been established with a high accuracy. High sig...

cis-Diamminediiodoplatinum (cis-DIDP) is a cisplatin-like anticancer drug with higher anticancer activity, but lower stability and price than cisplatin. In this study, a cis-DIDP carrier system based on micro-sized stearic acid was prepared by an emulsion solvent evaporation method. The maximum drug loading capacity of cis-DIDP-loaded solid lipid nanoparticles was 22.03%, and their encapsulatio...

This paper assessed crop farmers’ access and utilization of climate information services (CIS) impact CIS use on yields in Ebonyi State, Nigeria. The multi-stage sampling procedure was used to select 405 farmers from the data were collected through a survey using questionnaire. We employed descriptive statistics, endogenous treatment effect, Heckman probit selection model analyze collected. res...

BACKGROUND AND PURPOSE Many studies have observed atrophy and abnormal diffusion within the CC in MS. However, few studies have addressed whether such abnormalities appear at the earliest stage of MS, especially in CIS. In this study, we aimed to investigate the CC integrity and patterns of CC abnormalities in CIS with diffusion tensor group tractography. MATERIALS AND METHODS First, probabil...

This two-stage study was undertaken to assess the extent and nature of Critical Incident Stress (CIS) amongst frontline staff in a large ambulance service in Ireland. In Stage One, 63% (112/180) of participants completed a Screening Questionnaire and the GHQ-12. In Stage Two, 27 participants, who had experienced a critical incident (CI) during the previous year completed several measures to ass...

adenocarcinoma in situ is one of the premalignant lesions of the cervix and its incidence is believed to be increasing while the pathogenesis of the disease is not clearly understood. management of adenocarcinoma in situ (ais) unlike carcinoma in situ (cis) has not been clearly described in the current literature. here we describe conservative management and serial  olposcopy of two pregnant wo...

Objective. Diagnostic reliability of prenephroureterectomy ureteroscopy (PNU) for the detection of upper tract carcinoma in situ (CIS) remains unproven in particular and underreported in general. Methods. Patients who underwent radical nephroureterectomy (RNU) in a large multicentre retrospective study for upper tract transitional cell carcinoma (UT-TCC) between January 2002 and December 2013 w...